The discovery of the biological functions of the interleukin-23/-17 axis led to the identification
of IL-23 and IL-17 as important participants in the pathogenesis of several immune-mediated …

Interleukin-17 (IL-17) is a cytokine which elicits protection against extracellular bacterial and
fungal infections and which plays important roles in inflammation. However, when produced …

Advancements in the immunopathogenesis of psoriasis have identified interleukin (IL)‐23
and IL‐17 as fundamental contributors in the immune pathways of the disease. Leveraging …

Psoriasis and psoriatic arthritis (PsA) are pathophysiological enigmas among rheumatic
diseases. Substantial clinical advances have been made with new therapy targeting …

The key role of interleukin-17 (IL-17) and T helper 17 (TH17) cells in tissue inflammation,
autoimmunity and host defence led to the experimental targeting of these molecules in …

Psoriasis is a chronic, immune-mediated, inflammatory disease that is pathogenically driven
by proinflammatory cytokines. This article reviews the immunologic role of interleukin (IL)-17 …

Abstract Interleukin (IL)-12 and IL-23 play important roles in the development of
experimental autoimmune disease models and numerous afflictions affecting humans …

This review describes the IL-20 family of cytokines in rheumatoid arthritis (RA) and
spondyloartrhitits (SpA) including psoriatic arthritis. The IL-20 receptor (R) cytokines IL-19, IL …

Interleukin-17 (IL-17A) is a cytokine critical for the acute defence against extracellular
bacterial and fungal infections. Excess production during chronic inflammation has been …

The discovery that the IL-23–IL-17 immune pathway is involved in many models of
autoimmune disease has changed the concept of the role of T-helper cell subsets in the …