A cocktail of growth factors released from a heparin hyaluronic-acid hydrogel promotes the myogenic potential of human urine-derived stem cells in vivo
G Liu, R Wu, B Yang, Y Shi, C Deng, A Atala, S Mou… - Acta biomaterialia, 2020 - Elsevier
Traditional cell therapy technology relies on the maximum expansion of primary stem cells in
vitro, through multiple passages and potential differentiation protocols, in order to generate …
vitro, through multiple passages and potential differentiation protocols, in order to generate …
Skeletal myogenic differentiation of urine-derived stem cells and angiogenesis using microbeads loaded with growth factors
To provide site-specific delivery and targeted release of growth factors to implanted urine-
derived stem cells (USCs), we prepared microbeads of alginate containing growth factors …
derived stem cells (USCs), we prepared microbeads of alginate containing growth factors …
The effect of urine-derived stem cells expressing VEGF loaded in collagen hydrogels on myogenesis and innervation following after subcutaneous implantation in …
G Liu, X Wang, X Sun, C Deng, A Atala, Y Zhang - Biomaterials, 2013 - Elsevier
Impairment of sphincter muscles or their neural and vascular support leads to stress urinary
incontinence. The aim of this study was to determine the role of urine-derived stem cells …
incontinence. The aim of this study was to determine the role of urine-derived stem cells …
Enhanced survival and engraftment of transplanted stem cells using growth factor sequestering hydrogels
AK Jha, KM Tharp, J Ye, JL Santiago-Ortiz… - Biomaterials, 2015 - Elsevier
We have generated a bioinspired tunable system of hyaluronic acid (HyA)-based hydrogels
for Matrix-Assisted Cell Transplantation (MACT). With this material, we have independently …
for Matrix-Assisted Cell Transplantation (MACT). With this material, we have independently …
Bioprinted nanocomposite hydrogels: A proposed approach to functional restoration of skeletal muscle and vascular tissue following volumetric muscle loss
Musculoskeletal conditions are the highest contributor to global disability, accounting for
16% of all ages lived with disability. Volumetric muscle loss (VML) is classified as significant …
16% of all ages lived with disability. Volumetric muscle loss (VML) is classified as significant …
[HTML][HTML] An in vitro study to assess the effect of hyaluronan-based gels on muscle-derived cells: Highlighting a new perspective in regenerative medicine
A Stellavato, L Abate, V Vassallo, M Donniacuo… - PLoS …, 2020 - journals.plos.org
Hyaluronan (HA) is a nonsulfated glycosaminoglycan that has been widely used for
biomedical applications. Here, we have analyzed the effect of HA on the rescue of primary …
biomedical applications. Here, we have analyzed the effect of HA on the rescue of primary …
Biofunctional hydrogels for skeletal muscle constructs
AS Salimath, AJ García - Journal of tissue engineering and …, 2016 - Wiley Online Library
Hydrogel scaffolds encapsulating C2C12 mouse skeletal muscle cells have been
engineered as in vitro constructs towards regenerative medicine therapies for the …
engineered as in vitro constructs towards regenerative medicine therapies for the …
The use of a hydrogel matrix as a cellular delivery vehicle in future cell-based therapies: biological and non-biological considerations
TI Zarembinski, WP Tew, SK Atzet - Regenerative Medicine and …, 2011 - books.google.com
Cell therapy is defined as the minimally-invasive delivery of therapeutic cells into a human
host to repair damaged or diseased tissue (s). Its long-term goal is to reduce the current …
host to repair damaged or diseased tissue (s). Its long-term goal is to reduce the current …
Muscle stem cell intramuscular delivery within hyaluronan methylcellulose improves engraftment efficiency and dispersion
Adult skeletal muscle tissue harbors the capacity for self-repair due to the presence of tissue
resident muscle stem cells (MuSCs). Advances in the area of prospective MuSC isolation …
resident muscle stem cells (MuSCs). Advances in the area of prospective MuSC isolation …
[HTML][HTML] Urine-derived stem cells for epithelial tissues reconstruction and wound healing
X Yin, Q Li, PM McNutt, Y Zhang - Pharmaceutics, 2022 - mdpi.com
Epithelial tissue injury can occur on any surface site of the body, particularly in the skin or
urethral mucosa tissue, due to trauma, infection, inflammation, and toxic compounds. Both …
urethral mucosa tissue, due to trauma, infection, inflammation, and toxic compounds. Both …