Tuberculosis (TB) elimination requires innovative approaches. The new Global Tuberculosis
Network (GTN) aims to conduct research on key unmet therapeutic and diagnostic needs in …

Tuberculosis infection (TBI) is defined as a state of infection in which individuals host live
Mycobacterium tuberculosis with or without clinical signs of active TB. It is now understood …

Introduction: Tuberculosis (TB) remains the leading cause of death from a curable infectious
disease; drug-resistant TB threatens to dismantle all prior gains in global control. Suboptimal …

Optimization of dosing strategies and companion drugs prior to Phase III trials is currently a
critical obstacle in the development of new anti-tuberculosis drugs. Pharmacokinetic …

The World Health Organization (WHO) has produced this WHO operational handbook on
tuberculosis to provide practical advice to complement the latest WHO consolidated …

Tuberculosis (TB) kills more people than any other infectious disease. Challenges for
developing better treatments include the complex pathology due to within-host immune …

Despite two decades of intensified research to understand and cure tuberculosis disease,
biological uncertainties remain and hamper progress. However, owing to collaborative …

Current tuberculosis (TB) treatment is based on a combination of drugs that were developed
mostly in the central decades of the last century. Cure rates are high for drug sensitive …

Background Development of new, effective, and affordable tuberculosis (TB) therapies has
been identified as a critical priority for global TB control. As new candidates emerge from the …

The introduction of new rapid diagnostic tools for tuberculosis (TB) and the promising TB
drugs pipeline together with the development of a new World Health Organization Strategy …