In-vivo selection of an azole-resistant petite mutant of Candida glabrata

JP Bouchara, R Zouhair… - Journal of medical …, 2000 - microbiologyresearch.org
Two isolates of Candida glabrata from the same stool sample from a bone marrow transplant
recipient treated with fluconazole, and designated 1084-L for large colonies on yeast extract …

Characterization of an azole-resistant Candida glabrata isolate

H Vanden Bossche, P Marichal, FC Odds… - Antimicrobial Agents …, 1992 - Am Soc Microbiol
A Candida (Torulopsis) glabrata strain (B57149) became resistant to fluconazole after a
patient carrying the organism was treated with the drug at 400 mg once daily for 9 days …

[HTML][HTML] Fluconazole exposure rather than clonal spreading is correlated with the emergence of Candida glabrata with cross-resistance to triazole antifungal agents

TC Chen, YH Chen, YC Chen, PL Lu - The Kaohsiung journal of medical …, 2012 - Elsevier
The emergence of antifungal resistance in Candida species has raised concern in recent
years, especially resistance toward triazole. Several newer triazole antifungal agents have …

Candida glabrata: In vitro Susceptibility of 84 Isolates to Eight Antifungal Agents

A Arias, MP Arevalo, A Andreu, C Rodriguez, A Sierra - Chemotherapy, 1996 - karger.com
The in vitro susceptibility of 84 isolates of Candida glabrata from patients treated at the
University Hospital of the Canary islands to eight antifungal agents (amphotericin B …

Rapid Acquisition of Stable Azole Resistance by Candida glabrata Isolates Obtained before the Clinical Introduction of Fluconazole

A Borst, MT Raimer, DW Warnock… - Antimicrobial agents …, 2005 - Am Soc Microbiol
Five azole-susceptible Candida glabrata isolates obtained before 1975 became resistant to
fluconazole, itraconazole, and voriconazole within 4 days of in vitro fluconazole exposure …

Multiple Patterns of Resistance to Fluconazole in Candida glabrata Isolates from a Patient with Oropharyngeal Candidiasis Receiving Head and Neck Radiation

SW Redding, WR Kirkpatrick, S Saville… - Journal of clinical …, 2003 - Am Soc Microbiol
Candida glabrata has emerged in recent years as a significant cause of systemic fungal
infection. We have previously reported on the first three patients receiving radiation for head …

Molecular biological characterization of an azole-resistant Candida glabrata isolate

P Marichal, H Vanden Bossche, FC Odds… - Antimicrobial agents …, 1997 - Am Soc Microbiol
Two isolates of Candida glabrata, one susceptible and one resistant to azole antifungals,
were previously shown to differ in quantity and activity of the cytochrome P-450 14alpha …

Prospective, Multicenter Surveillance Study of Candida glabrata: Fluconazole and Itraconazole Susceptibility Profiles in Bloodstream, Invasive, and Colonizing Strains and …

A Safdar, V Chaturvedi, BS Koll… - Antimicrobial agents …, 2002 - Am Soc Microbiol
Since the 1990s, the substantial increase in the rate of Candida glabrata infections has
become a serious problem. As most C. glabrata infections arise from the host's endogenous …

In-vitro resistance to azoles associated with mitochondrial DNA deficiency in Candida glabrata

A Defontaine, JP Bouchara… - Journal of medical …, 1999 - microbiologyresearch.org
A commercially available disk diffusion procedure was used in a large-scale study to
evaluate the susceptibility of a wide range of Candida isolates to polyenes and azoles. With …

Clinical Significance of Azole Antifungal Drug Cross-Resistance in Candida glabrata

AA Panackal, JL Gribskov, JF Staab… - Journal of clinical …, 2006 - Am Soc Microbiol
Candida glabrata, which can become resistant to fluconazole, is a common cause of
bloodstream infection. This study was performed to determine the significance of cross …