CpG oligodeoxynucleotides (ODNs) bind to and activate Toll-like receptor 9 (TLR9),
initiating an innate immune response that supports the subsequent development of adaptive …

CpG Oligonucleotides (ODN) are immunomodulatory synthetic oligonucleotides specifically
designed to stimulate Toll-like receptor 9. TLR9 is expressed on human plasmacytoid …

CpG Oligonucleotides (ODN) are immunomodulatory synthetic oligonucleotides designed to
specifically agonize Toll-like receptor 9. Here, we review recent progress in understanding …

CpG oligodeoxynucleotides (ODN) activate the immune system and are promising
immunotherapeutic agents against infectious diseases, allergy/asthma and cancer. It has …

Synthetic oligonucleotides (ODN) that express unmethylated “CpG motifs” trigger cells that
express Toll-like receptor 9. In humans this includes plasmacytoid dendritic cells and B cells …

Toll-like receptor 9 (TLR9) agonists have demonstrated substantial potential as vaccine
adjuvants, and as mono-or combination therapies for the treatment of cancer and infectious …

Cytosine-phosphorothioate-guanine oligodeoxynucleotides (CpG ODN) have shown
significant potential for treatment of a wide variety of diseases including cancer. CpG ODN …

Distinct immune responses are required for efficient elimination of different pathogens.
Programming of the desired type of immune response by safe non-replicating vaccines …

Vertebrate toll-like receptors (TLRs) sense invading pathogens by recognizing bacterial and
viral structures and, as a result, activate innate and adaptive immune responses. Ten human …

The innate immune system detects pathogens by the presence of highly conserved
pathogen-expressed molecules, which trigger host immune defenses. Toll-like receptor …