Threat-induced modulation of hippocampal and striatal memory systems during navigation of a virtual environment
The brain is composed of multiple memory systems that mediate distinct types of navigation.
The hippocampus is important for encoding and retrieving allocentric spatial cognitive maps …
The hippocampus is important for encoding and retrieving allocentric spatial cognitive maps …
Negative emotional experiences during navigation enhance parahippocampal activity during recall of place information
It is known that the parahippocampal cortex is involved in object–place associations in
spatial learning, but it remains unknown whether activity within this region is modulated by …
spatial learning, but it remains unknown whether activity within this region is modulated by …
Acute stress switches spatial navigation strategy from egocentric to allocentric in a virtual Morris water maze
Stress and stress hormones are known to influence the function of the hippocampus, a brain
structure critical for cognitive-map-based, allocentric spatial navigation. The caudate …
structure critical for cognitive-map-based, allocentric spatial navigation. The caudate …
The relationships between trait anxiety, place recognition memory, and learning strategy
WR Hawley, EM Grissom, GP Dohanich - Behavioural brain research, 2011 - Elsevier
Rodents learn to navigate mazes using various strategies that are governed by specific
regions of the brain. The type of strategy used when learning to navigate a spatial …
regions of the brain. The type of strategy used when learning to navigate a spatial …
[PDF][PDF] Stress disrupts human hippocampal-prefrontal function during prospective spatial navigation and hinders flexible behavior
The ability to anticipate and flexibly plan for the future is critical for achieving goal-directed
outcomes. Extant data suggest that neural and cognitive stress mechanisms may disrupt …
outcomes. Extant data suggest that neural and cognitive stress mechanisms may disrupt …
The impact of threat of shock-induced anxiety on the neural substrates of memory encoding and retrieval
M Garibbo, J Aylward… - Social cognitive and …, 2019 - academic.oup.com
Dysfunctional memory processes are widely reported in anxiety disorders, but the
underlying neurocognitive mechanisms are unclear. Recent work shows that the impact of …
underlying neurocognitive mechanisms are unclear. Recent work shows that the impact of …
Location-dependent threat and associated neural abnormalities in clinical anxiety
Anxiety disorders are characterized by maladaptive defensive responses to distal or
uncertain threats. Elucidating neural mechanisms of anxiety is essential to understand the …
uncertain threats. Elucidating neural mechanisms of anxiety is essential to understand the …
Gray matter differences correlate with spontaneous strategies in a human virtual navigation task
Young healthy participants spontaneously use different strategies in a virtual radial maze, an
adaptation of a task typically used with rodents. Functional magnetic resonance imaging …
adaptation of a task typically used with rodents. Functional magnetic resonance imaging …
Disentangling hippocampal and amygdala contribution to human anxiety-like behavior
Anxiety comprises a suite of behaviors to deal with potential threat and is often modeled in
approach–avoidance conflict tasks. Collectively, these tests constitute a predominant …
approach–avoidance conflict tasks. Collectively, these tests constitute a predominant …
Reactivation of an aversive memory modulates learning strategy preference in male rats
WR Hawley, EM Grissom, JM Patel, KS Hodges… - Stress, 2013 - Taylor & Francis
Reminders of an aversive event adversely impact retrieval of hippocampus-dependent
memories and exacerbate stress-induced levels of anxiety. Interestingly, stress and anxiety …
memories and exacerbate stress-induced levels of anxiety. Interestingly, stress and anxiety …