[HTML][HTML] Exosomes: a novel strategy for treatment and prevention of diseases

J Wang, X Sun, J Zhao, Y Yang, X Cai, J Xu… - Frontiers in …, 2017 - frontiersin.org
An “exosome” is a nanoscale membrane vesicle derived from cell endocytosis that functions
as an important intercellular communication mediator regulating the exchange of proteins …

[HTML][HTML] Biology, pathophysiological role, and clinical implications of exosomes: a critical appraisal

AT Jan, S Rahman, S Khan, SA Tasduq, I Choi - Cells, 2019 - mdpi.com
Exosomes are membrane-enclosed entities of endocytic origin, which are generated during
the fusion of multivesicular bodies (MVBs) and plasma membranes. Exosomes are released …

[HTML][HTML] Emerging roles of exosomes in normal and pathological conditions: new insights for diagnosis and therapeutic applications

J De Toro, L Herschlik, C Waldner… - Frontiers in …, 2015 - frontiersin.org
From the time when they were first described in the 1970s by the group of Johnstone and
Stahl, exosomes are a target of constant research. Exosomes belong to the family of …

[HTML][HTML] The exosome journey: from biogenesis to regulation and function in cancers

Y Li, L Meng, B Li, Y Li, T Shen, B Zhao - Journal of Oncology, 2022 - hindawi.com
Exosomes are a type of small endosomal-derived vesicles ranging from 30 to 150 nm, which
can serve as functional mediators in cell-to-cell communication and various physiological …

The distinct roles of exosomes in innate immune responses and therapeutic applications in cancer

J Rezaie, T Etemadi, M Feghhi - European journal of pharmacology, 2022 - Elsevier
The innate immune system is one of the major constituents of the host's defense against
invading pathogens and extracellular vesicles (EVs) are involved in regulating its …

[HTML][HTML] Roles of exosomes in cancer chemotherapy resistance, progression, metastasis and immunity, and their clinical applications

X Wang, Y Zhou, K Ding - International journal of …, 2021 - spandidos-publications.com
Exosomes are a type of vesicle that are secreted by cells, with a diameter of 40‑100 nm, and
that appear as a cystic shape under an electron microscope. Exosome cargo includes a …

[HTML][HTML] Functions and therapeutic roles of exosomes in cancer

JA Tickner, AJ Urquhart, SA Stephenson… - Frontiers in …, 2014 - frontiersin.org
The role of exosomes in cancer development has become the focus of much research, due
to the many emerging roles possessed by exosomes. These micro-vesicles that are …

[HTML][HTML] Exosomes, their biogenesis and role in inter-cellular communication, tumor microenvironment and cancer immunotherapy

KK Jella, TH Nasti, Z Li, SR Malla, ZS Buchwald… - Vaccines, 2018 - mdpi.com
Exosomes are extracellular vesicles ranging from 30 to 150 nm in diameter that contain
molecular constituents of their host cells. They are released from different types of cells …

[HTML][HTML] From pathogenesis to clinical application: insights into exosomes as transfer vectors in cancer

W Xu, Z Yang, N Lu - Journal of Experimental & Clinical Cancer Research, 2016 - Springer
Exosomes are nanoscale extracellular membrane vesicles that are created by the fusion of
an intracellular multivesicular body with the cell membrane. They are widely distributed in …

Role of exosomes in tumour growth, chemoresistance and immunity: state-of-the-art

SM Hosseinikhah, F Gheybi, SA Moosavian… - Journal of Drug …, 2023 - Taylor & Francis
Cancer is one of the most lethal diseases, and limited available treatment options contribute
to its high mortality rate. Exosomes are considered membrane-bound nanovesicles that …