Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

HJ Watson, Z Yilmaz, LM Thornton, C Hübel… - Nature …, 2019 - nature.com
Characterized primarily by a low body-mass index, anorexia nervosa is a complex and
serious illness, affecting 0.9–4% of women and 0.3% of men,–, with twin-based heritability …

Genomics of body fat percentage may contribute to sex bias in anorexia nervosa

C Hübel, HA Gaspar, JRI Coleman… - American Journal of …, 2019 - Wiley Online Library
Anorexia nervosa (AN) occurs nine times more often in females than in males. Although
environmental factors likely play a role, the reasons for this imbalanced sex ratio remain …

A genome-wide association study of anorexia nervosa

V Boraska, CS Franklin, JAB Floyd, LM Thornton… - Molecular …, 2014 - nature.com
Anorexia nervosa (AN) is a complex and heritable eating disorder characterized by
dangerously low body weight. Neither candidate gene studies nor an initial genome-wide …

Significant locus and metabolic genetic correlations revealed in genome-wide association study of anorexia nervosa

L Duncan, Z Yilmaz, H Gaspar… - American journal of …, 2017 - Am Psychiatric Assoc
Objective: The authors conducted a genome-wide association study of anorexia nervosa
and calculated genetic correlations with a series of psychiatric, educational, and metabolic …

The anorexia nervosa genetics initiative (ANGI): overview and methods

LM Thornton, MA Munn-Chernoff, JH Baker… - Contemporary Clinical …, 2018 - Elsevier
Background Genetic factors contribute to anorexia nervosa (AN); and the first genome-wide
significant locus has been identified. We describe methods and procedures for the Anorexia …

One size does not fit all. Genomics differentiates among anorexia nervosa, bulimia nervosa, and binge‐eating disorder

C Hübel, M Abdulkadir, M Herle… - … Journal of Eating …, 2021 - Wiley Online Library
Objective Genome‐wide association studies have identified multiple genomic regions
associated with anorexia nervosa. No genome‐wide studies of other eating disorders, such …

Genetic variants associated with disordered eating

TD Wade, S Gordon, S Medland… - … Journal of Eating …, 2013 - Wiley Online Library
Objective Although the genetic contribution to the development of anorexia nervosa (AN)
has long been recognized, there has been little progress relative to other psychiatric …

Genetics of eating disorders

A Hinney, AL Volckmar - Current psychiatry reports, 2013 - Springer
Disordered eating behavior is the core symptom of the complex disorders anorexia nervosa
and bulimia nervosa. Twin and family studies derive high heritability estimates. Hence …

[PDF][PDF] Evidence for a susceptibility gene for anorexia nervosa on chromosome 1

DE Grice, KA Halmi, MM Fichter, M Strober… - The American Journal of …, 2002 - cell.com
Eating disorders, such as anorexia nervosa (AN), have a significant genetic component. In
the current study, a genomewide linkage analysis of 192 families with at least one affected …

Examination of the shared genetic basis of anorexia nervosa and obsessive–compulsive disorder

Z Yilmaz, M Halvorsen, J Bryois, D Yu… - Molecular …, 2020 - nature.com
Anorexia nervosa (AN) and obsessive–compulsive disorder (OCD) are often comorbid and
likely to share genetic risk factors. Hence, we examine their shared genetic background …