Activation of NK1 receptor of trigeminal root ganglion via substance P paracrine mechanism contributes to the mechanical allodynia in the temporomandibular joint …

M Takeda, T Tanimoto, M Nasu, M Ikeda, J Kadoi… - Pain, 2005 - journals.lww.com
The aim of this study was to investigate whether under in vivo conditions,
temporomandibular joint (TMJ) inflammation alters the excitability of Aβ-trigeminal root …

Temporomandibular joint inflammation potentiates the excitability of trigeminal root ganglion neurons innervating the facial skin in rats

M Takeda, T Tanimoto, M Ikeda… - Journal of …, 2005 - journals.physiology.org
The aim of this study was to test the hypothesis that temporomandibular joint (TMJ)
inflammation alters the excitability of trigeminal root ganglion (TRG) neurons innervating the …

Enhanced excitability of rat trigeminal root ganglion neurons via decrease in A-type potassium currents following temporomandibular joint inflammation

M Takeda, T Tanimoto, M Ikeda, M Nasu, J Kadoi… - Neuroscience, 2006 - Elsevier
The aim of the present study was to investigate the effect of temporomandibular joint
inflammation on the excitability of trigeminal root ganglion neurons innervating the …

Temporomandibular joint inflammation decreases the voltage-gated K+ channel subtype 1.4-immunoreactivity of trigeminal ganglion neurons in rats

M Takeda, T Tanimoto, M Nasu, S Matsumoto - European journal of pain, 2008 - Elsevier
Voltage-gated K+ (Kv) channels are one of the important physiological regulators of the
membrane potentials in excitable cells, including sensory ganglion neurons. The aim of the …

Involvement of trigeminal ganglionic Nav1.7 in hyperalgesia of inflamed temporomandibular joint is dependent on ERK1/2 phosphorylation of glial cells in rats

RY Bi, XX Kou, Z Meng, XD Wang… - European Journal of …, 2013 - Wiley Online Library
Background Inflammation is a major cause of temporomandibular disorder‐related pain. The
N av1. 7 sodium channel has a critical function in pain perceptions. However, whether and …

[HTML][HTML] P2X3 receptor upregulation in trigeminal ganglion neurons through TNFα production in macrophages contributes to trigeminal neuropathic pain in rats

M Koizumi, S Asano, A Furukawa, Y Hayashi… - The Journal of …, 2021 - Springer
Background Trigeminal neuralgia is a characteristic disease that manifests as orofacial
phasic or continuous severe pain triggered by innocuous orofacial stimulation; its …

Modulation of paratrigeminal nociceptive neurons following temporomandibular joint inflammation in rats

Y Yamazaki, K Ren, M Shimada, K Iwata - Experimental neurology, 2008 - Elsevier
To evaluate the involvement of paratrigeminal nucleus (Pa5) nociceptive neurons in
temporomandibular joint (TMJ) inflammation-induced pain and its autonomic correlates, we …

[HTML][HTML] CENTRAL ROLE OF PROTEIN KINASE A IN PROMOTING TRIGEMINAL NOCICEPTION IN AN IN VIVO MODEL OF TEMPOROMANDIBULAR JOINT …

LK Koop, JL Hawkins, LE Cornelison… - … of oral & facial pain and …, 2017 - ncbi.nlm.nih.gov
Aims To investigate cellular changes in the spinal trigeminal nucleus (STN) and trigeminal
ganglion associated with trigeminal nociception mediated by inflammation in the …

Contribution of activated interleukin receptors in trigeminal ganglion neurons to hyperalgesia via satellite glial interleukin-1β paracrine mechanism

M Takeda, M Takahashi, S Matsumoto - Brain, behavior, and immunity, 2008 - Elsevier
The present study investigated whether under in vivo conditions, inflammation alters the
excitability of nociceptive Aδ-trigeminal ganglion (TRG) neurons innervating the facial skin …

Nerve terminals extend into the temporomandibular joint of adjuvant arthritic rats

M Shinoda, T Honda, N Ozaki, H Hattori… - European Journal of …, 2003 - Elsevier
The innervation of the temporomandibular joint (TMJ) has attracted particular interest
because of the close association with complex mandibular movement. Although the …