[HTML][HTML] Effects of adenosine A2a receptor agonist and antagonist on cerebellar nuclear factor-kB expression preceded by MDMA toxicity

F Kermanian, M Soleimani, B Pourheydar… - Medical Journal of the …, 2014 - ncbi.nlm.nih.gov
Background: Adenosine is an endogenous purine nucleoside that has a neuromodulatory
role in the central nervous system. The amphetamine derivative (±)-3, 4 …

Effects of adenosine A2a receptor agonist and antagonist on hippocampal nuclear factor-kB expression preceded by MDMA toxicity

F Kermanian, M Soleimani, A Ebrahimzadeh… - Metabolic brain …, 2013 - Springer
There is an abundance of evidence showing that repeated use of 3, 4-
methlylenedioxymethamphetamine (MDMA; ecstasy) is associated with brain dysfunction …

Adenosine A2a receptors activate Nuclear Factor-Kappa B (NF-κB) in rat hippocampus after exposure to different doses of MDMA

F Kermanian, M Mehdizadeh, M Soleimani… - Molecular & cellular …, 2014 - Springer
Abstract MDMA (3, 4-methylenedioxy-N-methamphetamine) as an empathogenic drug
causes neurotoxicity although the mechanisms have not been fully elucidated. The A2a …

The role of adenosine receptor agonist and antagonist on Hippocampal MDMA detrimental effects; a structural and behavioral study

F Kermanian, M Mehdizadeh, M Soleimani… - Metabolic brain …, 2012 - Springer
There is abundant evidence showing that repeated use of MDMA (3, 4-
Methylenedioxymethamphetamine, ecstasy) has been associated with depression, anxiety …

[HTML][HTML] The role of adenosine A1 and A2A receptors in the caffeine effect on MDMA-induced DA and 5-HT release in the mouse striatum

AM Górska, K Gołembiowska - Neurotoxicity research, 2015 - Springer
Methylenedioxymethamphetamine (MDMA,“ecstasy”) popular as a designer drug is often
used with caffeine to gain a stronger stimulant effect. MDMA induces 5-HT and DA release …

Effect of chronic manganese treatment on adenosine tissue levels and adenosine A2a receptor binding in diverse regions of mouse brain

V Villalobos, J Suárez, J Estévez, E Novo… - Neurochemical …, 2001 - Springer
In the present study the effects of chronic manganese (Mn) treatment on adenosine A 2a
receptor binding in mouse brain have been assessed. Male albino mice were divided in two …

[HTML][HTML] The mediating role of A2A adenosine receptors in the mitochondrial pathway of apoptotic hippocampal cell death, following the administration of MDMA in rat

M Bakhshayesh, F Golab, F Kermanian… - Basic and clinical …, 2017 - ncbi.nlm.nih.gov
Methods: The current study used 40 Sprague-Dawley rats, weighted 200 to 250 g.
Experiments were performed in four groups, each containing 10 rats. The first group of rats …

[HTML][HTML] MDMA and the Brain: A Short Review on the Role of Neurotransmitters in Neurotoxicity

NS Mustafa, NHA Bakar, N Mohamad… - Basic and clinical …, 2020 - ncbi.nlm.nih.gov
Abstract N-Methyl-3, 4-methylenedioxyamphetamine (MDMA), or ecstasy is a recreational
drug of abuse. It is a synthetic substance that affects the body's systems, which its …

The A2a adenosine receptor modulates the reinforcement efficacy and neurotoxicity of MDMA

J Ruiz-Medina, C Ledent, O Carretón… - Journal of …, 2011 - journals.sagepub.com
Adenosine is an endogenous purine nucleoside that plays a neuromodulatory role in the
central nervous system. A2a adenosine receptors have been involved in reward-related …

[HTML][HTML] The effect of 3, 4-methylenedioxymethamphetamine on expression of neurotrophic factors in hippocampus of male rats

SS Asl, MBH Shariati, M Medizadeh… - Medical Journal of the …, 2017 - ncbi.nlm.nih.gov
Background: 3, 4-methylenedioxymethamphetamine (MDMA) is a chemical derivative of
amphetamine that can induce learning and memory impairment. Due to the effect of …