Bayesian data integration and variable selection for pan-cancer survival prediction using protein expression data
Accurate prognostic prediction using molecular information is a challenging area of
research, which is essential to develop precision medicine. In this paper, we develop …
research, which is essential to develop precision medicine. In this paper, we develop …
Bayesian hierarchical varying-sparsity regression models with application to cancer proteogenomics
Identifying patient-specific prognostic biomarkers is of critical importance in developing
personalized treatment for clinically and molecularly heterogeneous diseases such as …
personalized treatment for clinically and molecularly heterogeneous diseases such as …
Integration of survival and binary data for variable selection and prediction: a Bayesian approach
AK Maity, RJ Carroll, BK Mallick - Journal of the Royal Statistical …, 2019 - academic.oup.com
We consider the problem where the data consist of a survival time and a binary outcome
measurement for each individual, as well as corresponding predictors. The goal is to select …
measurement for each individual, as well as corresponding predictors. The goal is to select …
Bayesian ensemble methods for survival prediction in gene expression data
V Bonato, V Baladandayuthapani, BM Broom… - …, 2011 - academic.oup.com
Abstract Motivation: We propose a Bayesian ensemble method for survival prediction in high-
dimensional gene expression data. We specify a fully Bayesian hierarchical approach …
dimensional gene expression data. We specify a fully Bayesian hierarchical approach …
CASPAR: a hierarchical bayesian approach to predict survival times in cancer from gene expression data
L Kaderali, T Zander, U Faigle, J Wolf… - …, 2006 - academic.oup.com
Motivation: DNA microarrays allow the simultaneous measurement of thousands of gene
expression levels in any given patient sample. Gene expression data have been shown to …
expression levels in any given patient sample. Gene expression data have been shown to …
Pathway-structured predictive model for cancer survival prediction: a two-stage approach
Heterogeneity in terms of tumor characteristics, prognosis, and survival among cancer
patients has been a persistent problem for many decades. Currently, prognosis and …
patients has been a persistent problem for many decades. Currently, prognosis and …
Integrating biological knowledge with gene expression profiles for survival prediction of cancer
X Chen, L Wang - Journal of Computational Biology, 2009 - liebertpub.com
Due to the large variability in survival times between cancer patients and the plethora of
genes on microarrays unrelated to outcome, building accurate prediction models that are …
genes on microarrays unrelated to outcome, building accurate prediction models that are …
[HTML][HTML] Discovery of pathway-independent protein signatures associated with clinical outcome in human cancer cohorts
MM Konaté, MC Li, LM McShane, Y Zhao - Scientific Reports, 2022 - nature.com
Proteomic data provide a direct readout of protein function, thus constituting an information-
rich resource for prognostic and predictive modeling. However, protein array data may not …
rich resource for prognostic and predictive modeling. However, protein array data may not …
Gaussian process regression for survival time prediction with genome-wide gene expression
Predicting the survival time of a cancer patient based on his/her genome-wide gene
expression remains a challenging problem. For certain types of cancer, the effects of gene …
expression remains a challenging problem. For certain types of cancer, the effects of gene …
[HTML][HTML] Gsslasso Cox: a Bayesian hierarchical model for predicting survival and detecting associated genes by incorporating pathway information
Background Group structures among genes encoded in functional relationships or biological
pathways are valuable and unique features in large-scale molecular data for survival …
pathways are valuable and unique features in large-scale molecular data for survival …