Bayesian data integration and variable selection for pan-cancer survival prediction using protein expression data

AK Maity, A Bhattacharya, BK Mallick… - …, 2020 - academic.oup.com
Accurate prognostic prediction using molecular information is a challenging area of
research, which is essential to develop precision medicine. In this paper, we develop …

Bayesian hierarchical varying-sparsity regression models with application to cancer proteogenomics

Y Ni, FC Stingo, MJ Ha, R Akbani… - Journal of the …, 2019 - Taylor & Francis
Identifying patient-specific prognostic biomarkers is of critical importance in developing
personalized treatment for clinically and molecularly heterogeneous diseases such as …

Integration of survival and binary data for variable selection and prediction: a Bayesian approach

AK Maity, RJ Carroll, BK Mallick - Journal of the Royal Statistical …, 2019 - academic.oup.com
We consider the problem where the data consist of a survival time and a binary outcome
measurement for each individual, as well as corresponding predictors. The goal is to select …

Bayesian ensemble methods for survival prediction in gene expression data

V Bonato, V Baladandayuthapani, BM Broom… - …, 2011 - academic.oup.com
Abstract Motivation: We propose a Bayesian ensemble method for survival prediction in high-
dimensional gene expression data. We specify a fully Bayesian hierarchical approach …

CASPAR: a hierarchical bayesian approach to predict survival times in cancer from gene expression data

L Kaderali, T Zander, U Faigle, J Wolf… - …, 2006 - academic.oup.com
Motivation: DNA microarrays allow the simultaneous measurement of thousands of gene
expression levels in any given patient sample. Gene expression data have been shown to …

Pathway-structured predictive model for cancer survival prediction: a two-stage approach

X Zhang, Y Li, T Akinyemiju, AI Ojesina, P Buckhaults… - Genetics, 2017 - academic.oup.com
Heterogeneity in terms of tumor characteristics, prognosis, and survival among cancer
patients has been a persistent problem for many decades. Currently, prognosis and …

Integrating biological knowledge with gene expression profiles for survival prediction of cancer

X Chen, L Wang - Journal of Computational Biology, 2009 - liebertpub.com
Due to the large variability in survival times between cancer patients and the plethora of
genes on microarrays unrelated to outcome, building accurate prediction models that are …

[HTML][HTML] Discovery of pathway-independent protein signatures associated with clinical outcome in human cancer cohorts

MM Konaté, MC Li, LM McShane, Y Zhao - Scientific Reports, 2022 - nature.com
Proteomic data provide a direct readout of protein function, thus constituting an information-
rich resource for prognostic and predictive modeling. However, protein array data may not …

Gaussian process regression for survival time prediction with genome-wide gene expression

AJ Molstad, L Hsu, W Sun - Biostatistics, 2021 - academic.oup.com
Predicting the survival time of a cancer patient based on his/her genome-wide gene
expression remains a challenging problem. For certain types of cancer, the effects of gene …

[HTML][HTML] Gsslasso Cox: a Bayesian hierarchical model for predicting survival and detecting associated genes by incorporating pathway information

Z Tang, S Lei, X Zhang, Z Yi, B Guo, JY Chen… - BMC …, 2019 - Springer
Background Group structures among genes encoded in functional relationships or biological
pathways are valuable and unique features in large-scale molecular data for survival …