hnRNP A2 is a protein involved in the trafficking pathway of HIV-1 genomic RNA

K Lévesque - 2005 - escholarship.mcgill.ca
ABSTRACT HIV-1 genomic RNA trafficking is an important event which remain unc1ear.
Different cellular proteins are involved in this process and the heterogeneous nuc1ear …

Trafficking of HIV‐1 RNA is mediated by heterogeneous nuclear ribonucleoprotein A2 expression and impacts on viral assembly

K Lévesque, M Halvorsen, L Abrahamyan… - Traffic, 2006 - Wiley Online Library
Few details are known about how the human immunodeficiency virus type 1 (HIV‐1)
genomic RNA is trafficked in the cytoplasm. Part of this process is controlled by the activity of …

[HTML][HTML] Human immunodeficiency virus type 1 (HIV-1) induces the cytoplasmic retention of heterogeneous nuclear ribonucleoprotein A1 by disrupting nuclear import …

A Monette, L Ajamian, M López-Lastra… - Journal of Biological …, 2009 - ASBMB
Human immunodeficiency virus type 1 (HIV-1) co-opts host proteins and cellular
machineries to its advantage at every step of the replication cycle. Here we show that HIV-1 …

Depletion of hnRNP A2/B1 overrides the nuclear retention of the HIV-1 genomic RNA

H Gordon, L Ajamian, F Valiente-Echeverrìa… - RNA biology, 2013 - Taylor & Francis
hnRNP A2 is a cellular protein that is important for nucleocytoplasmic and cytosolic
trafficking of the HIV-1 genomic RNA. Both hnRNP A2's interaction with HIV-1 RNA and its …

[HTML][HTML] A late role for the association of hnRNP A2 with the HIV-1 hnRNP A2 response elements in genomic RNA, Gag, and Vpr localization

V Bériault, JF Clément, K Lévesque, C LeBel… - Journal of Biological …, 2004 - ASBMB
Two cis-acting RNA trafficking sequences (heterogenous ribonucleoprotein A2 (hnRNP A2)-
response elements 1 and 2 or A2RE-1 and A2RE-2) have been identified in HIV-1 vpr and …

RNA trafficking signals in human immunodeficiency virus type 1

AJ Mouland, H Xu, H Cui, W Krueger… - … and cellular biology, 2001 - Taylor & Francis
Intracellular trafficking of retroviral RNAs is a potential mechanism to target viral gene
expression to specific regions of infected cells. Here we show that the human …

Impact of nuclear export pathway on cytoplasmic HIV-1 RNA transport mechanism and distribution

J Chen, C Umunnakwe, DQ Sun, OA Nikolaitchik… - MBio, 2020 - Am Soc Microbiol
ABSTRACT HIV-1 full-length RNA (referred to as HIV-1 RNA here) serves as the viral
genome in virions and as a template for Gag/Gag-Pol translation. We previously showed that …

Elucidation of the roles of the human immunodeficiency virus type 1 RNA trafficking signals in the viral replication cycle

V Bériault - 2003 - escholarship.mcgill.ca
Two RNA trafficking cis sequences (A2RE-1 and A2RE-2) were identified in HIV-1 RNA.
Their activity is assessed here during HIV-1 gene expression. Single point mutations in each …

HIV-1 remodels the nuclear pore complex

A Monette, N Panté, AJ Mouland - Journal of Cell Biology, 2011 - rupress.org
Human immunodeficiency virus type 1 (HIV-1) commandeers host cell proteins and
machineries for its replication. Our earlier work showed that HIV-1 induced the cytoplasmic …

[引用][C] hnRNP A2 EXPRESSION IS REQUIRED FOR HIV-1 GENOMIC RNA TRAFFICKING FROM THE MICROTUBULE ORGANIZING CENTER

K Lévesque, M Halvorsen, A Mouland