Colorectal cancer remains a major cancer diagnosis, and a cause of mortality worldwide
with screening and surveillance programs representing a significant healthcare commitment …

Colonoscopy offers incomplete protection from colorectal cancer, particularly in the right
colon. Part of this inadequacy may be related to serrated neoplasia. Serrated polyps of the …

elucidating the mechanisms involved in the serrated pathway to colorectal carcinogenesis, 5
including the observation that there was an overlap in the molecular features of …

Colorectal polyps have been traditionally classified as either hyperplastic or adenomatous,
with only the latter progressing to carcinoma. However, it is now recognized that certain …

Serrated polyps have long been considered to lack malignant potential but accumulating
data suggest that these lesions may cause up to one-third of all sporadic colorectal cancer …

Identification of the serrated neoplasia pathway has improved our understanding of the
pathogenesis of colorectal cancer (CRC). Insights include an increased recognition of the …

Serrated pathway polyps are a relatively new area of interest in the field of colorectal cancer
screening and prevention. Akin to conventional adenomas, some serrated polyps (SPs) …

Colorectal cancer (CRC) is considered a heterogeneous disease, both regarding
pathogenesis and clinical behaviour. Four decades ago, the adenoma–carcinoma pathway …

The concept of serrated colorectal neoplasia and a serrated pathway to colorectal cancer
(CRC) is relatively new and continuing to evolve, but it has become highly relevant to …

Serrated polyps (SPs) were once considered benign, clinically unimportant lesions.
However, it is now recognized that through the serrated neoplasia pathway (SNP), SPs play …