Absence of knockdown mutations in pyrethroid and DDT resistant populations of the main malaria vectors in Colombia

LI Orjuela, DA Álvarez-Diaz, JA Morales, N Grisales… - Malaria Journal, 2019 - Springer
Background Knockdown resistance (kdr) is a well-characterized target-site insecticide
resistance mechanism that is associated with DDT and pyrethroid resistance. Even though …

Molecular evidence for historical presence of knock-down resistance in Anopheles albimanus, a key malaria vector in Latin America

JC Lol, ME Castellanos, KA Liebman, A Lenhart… - Parasites & vectors, 2013 - Springer
Background Anopheles albimanus is a key malaria vector in the northern neotropics.
Current vector control measures in the region are based on mass distributions of long …

Knockdown resistance (kdr)-like mutations in the voltage-gated sodium channel of a malaria vector Anopheles stephensi and PCR assays for their detection

OP Singh, CL Dykes, M Lather, OP Agrawal, T Adak - Malaria journal, 2011 - Springer
Background Knockdown resistance (kdr) in insects, resulting from mutation (s) in the voltage-
gated sodium channel (vgsc) gene is one of the mechanisms of resistance against DDT and …

In vivo functional validation of the V402L voltage gated sodium channel mutation in the malaria vector An. gambiae

J Williams, R Cowlishaw, A Sanou… - Pest Management …, 2022 - Wiley Online Library
BACKGROUND Pyrethroids are the most widely used insecticides for the control of malaria
transmitting Anopheles gambiae mosquitoes and rapid increase in resistance to this …

A Primer-Introduced Restriction Analysis-Polymerase Chain Reaction Method to Detect Knockdown Resistance Mutations in Anopheles gambiae

F Janeira, JL Vicente, Y Kanganje… - Journal of medical …, 2014 - academic.oup.com
In the major malaria vector Anopheles gambiae Giles, two point mutations at the voltage-
gated sodium channel have been associated with knockdown resistance (kdr) to DDT and …

Mutations in the voltage-gated sodium channel gene of anophelines and their association with resistance to pyrethroids–a review

APB Silva, JMM Santos, AJ Martins - Parasites & vectors, 2014 - Springer
Constant and extensive use of chemical insecticides has created a selection pressure and
favored resistance development in many insect species worldwide. One of the most …

Contrasting patterns of gene expression indicate differing pyrethroid resistance mechanisms across the range of the New World malaria vector Anopheles albimanus

L Mackenzie-Impoinvil, GD Weedall, JC Lol, J Pinto… - PLoS …, 2019 - journals.plos.org
Decades of unmanaged insecticide use and routine exposure to agrochemicals have left
many populations of malaria vectors in the Americas resistant to multiple classes of …

Development of molecular assays to detect target-site mechanisms associated with insecticide resistance in malaria vectors from Latin America

JC Lol, D Castañeda, L Mackenzie-Impoinvil… - Malaria journal, 2019 - Springer
Background Malaria remains an important public health problem in Latin America, and the
development of insecticide resistance in malaria vectors poses a major threat to malaria …

First report of the F1534C mutation associated with cross-resistance to DDT and pyrethroids in Aedes aegypti from Colombia

MC Atencia, MJ Pérez, MC Jaramillo, SM Caldera… - Biomedica, 2016 - scielo.org.co
ATENCIA, María Claudia et al. First report of the F1534C mutation associated with cross-
resistance to DDT and pyrethroids in Aedes aegypti from Colombia. Biomédica [online] …

Detection of Knockdown Resistance Mutations in Anopheles sacharovi (Diptera: Culicidae) and Genetic Distance with Anopheles gambiae (Diptera: Culicidae) …

HÜ Lüleyap, D Alptekin, H Kasap… - Journal of medical …, 2002 - academic.oup.com
The knockdown resistance (kdr) mutation in the voltage-gated sodium channel gene
(VGSCG), an important resistance mechanism against pyrethroids, was studied in …