The Human ASCL2 Gene Escaping Genomic Imprinting and Its Expression Pattern

T Miyamoto, S Hasuike, Y Jinno, H Soejima… - Journal of assisted …, 2002 - Springer
The mouse achaete-scute homolog-2 gene (Ascl2 or Mash2) encodes a transcription factor
playing a role in the development of the trophoblast. The Ascl2 is an imprinted gene with …

Genomic cloning and localization to chromosome 11p15. 5 of the human achaete-scute homolog 2 (ASCL2)

T Miyamoto, Y Jinno, T Sasaki, Y Ikeda… - … and Genome Research, 1996 - karger.com
The mouse achaete-scute homolog-2 gene (Mash2), a member of the achaete-scute gene
family, encodes a transcription factor that plays an important role in the development of the …

A SacII polymorphism in the human ASCL2 (HASH2) gene region

T Miyamoto, Y Jinno, K Miura, K Sengoku… - Journal of human …, 1998 - nature.com
The mouse achaete-scute homolog-2 gene (Ascl2 or Mash2) encodes a transcription factor
playing a role in the development of the trophoblast. The Ascl2 gene is paternally imprinted …

[HTML][HTML] Increased dosage of the imprinted Ascl2 gene restrains two key endocrine lineages of the mouse Placenta

SJ Tunster, GI McNamara, HDJ Creeth, RM John - Developmental biology, 2016 - Elsevier
Imprinted genes are expressed primarily from one parental allele by virtue of a germ line
epigenetic process. Achaete-scute complex homolog 2 (Ascl2 aka Mash2) is a maternally …

[HTML][HTML] Partial loss of Ascl2 function affects all three layers of the mature placenta and causes intrauterine growth restriction

R Oh-McGinnis, AB Bogutz, L Lefebvre - Developmental biology, 2011 - Elsevier
Several imprinted genes have been implicated in the regulation of placental function and
embryonic growth. On distal mouse chromosome 7, two clusters of imprinted genes, each …

The Human Achaete-Scute Homologue 2 (ASCL2, HASH2) Maps to Chromosome 11p15.5, Close to IGF2 and is Expressed in Extravillus Trophoblasts

M Alders, M Hodges, AK Hadjantonakis… - Human molecular …, 1997 - academic.oup.com
Here we describe the cloning of the human Achaete Scute Homologue 2 (HASH2) gene,
officially designated ASCL2 (Achaete Scute complex like 2), a homologue of the …

Imprinted gene expression in fetal growth and development

L Lambertini, CJ Marsit, P Sharma, M Maccani, Y Ma… - Placenta, 2012 - Elsevier
Experimental studies showed that genomic imprinting is fundamental in fetoplacental
development by timely regulating the expression of the imprinted genes to overlook a set of …

Characterization of the placenta specific bovine mammalian achaete scute-like homologue 2 (Mash2) gene

DR Arnold, R Lefebvre, LC Smith - Placenta, 2006 - Elsevier
Mash2, a basic helix-loop-helix transcription factor, stimulates mononucleate trophoblast cell
proliferation and inhibits giant/binucleate cell formation. In mice, Mash2 is a maternally …

[HTML][HTML] Paternal imprinting of the SLC22A1LS gene located in the human chromosome segment 11p15.5

V Bajaj, M Markandaya, L Krishna, A Kumar - BMC genetics, 2004 - Springer
Background Genomic imprinting is an epigenetic chromosomal modification in the gametes
or zygotes that results in a non-random monoallelic expression of specific autosomal genes …

Structural and functional analysis of a 0.5-Mb chicken region orthologous to the imprinted mammalian Ascl2/Mash2–Igf2–H19 region

T Yokomine, H Shirohzu, W Purbowasito… - Genome …, 2005 - genome.cshlp.org
Previous studies revealed that Igf2 and Mpr/Igf2r are imprinted in eutherian mammals and
marsupials but not in monotremes or birds. Igf2 lies in a large imprinted cluster in eutherians …