Implantation of adipose-derived regenerative cells enhances ischemia-induced angiogenesis

K Kondo, S Shintani, R Shibata… - … , and vascular biology, 2009 - Am Heart Assoc
Objective—Therapeutic angiogenesis using autologous stem/progenitor cells represents a
novel strategy for severe ischemic diseases. Recent reports indicated that adipose tissues …

Transplantation of adipose stromal cells, but not mature adipocytes, augments ischemia-induced angiogenesis

M Sumi, M Sata, N Toya, K Yanaga, T Ohki, R Nagai - Life sciences, 2007 - Elsevier
Therapeutic angiogenesis has emerged as a promising therapy to treat patients with
ischemic diseases. Transplantation of bone marrow cells (BMCs) is reported to augment …

Human adipose tissue-derived mesenchymal stem cells improve postnatal neovascularization in a mouse model of hindlimb ischemia

MH Moon, SY Kim, YJ Kim, SJ Kim, JB Lee… - Cellular Physiology and …, 2006 - karger.com
Abstract Background/Aim: It has been reported that adipose tissue contain progenitor cells
with angiogenic potential and that therapy based on adipose tissuederived progenitor cells …

Therapeutic angiogenesis by autologous adipose-derived regenerative cells: comparison with bone marrow mononuclear cells

C Hao, S Shintani, Y Shimizu… - American Journal …, 2014 - journals.physiology.org
Transplantation of adipose-derived regenerative cell (ADRC) enhances ischemia-induced
angiogenesis, but the underlying mechanism remains unknown. Here, we compared the …

Plasticity of human adipose lineage cells toward endothelial cells: physiological and therapeutic perspectives

V Planat-Benard, JS Silvestre, B Cousin, M André… - Circulation, 2004 - Am Heart Assoc
Background—Adipose tissue development and remodeling are closely associated with the
growth of vascular network. We hypothesized that adipose tissue may contain progenitor …

Novel autologous cell therapy in ischemic limb disease through growth factor secretion by cultured adipose tissue–derived stromal cells

H Nakagami, K Maeda, R Morishita… - … , and vascular biology, 2005 - Am Heart Assoc
Objective—The delivery of autologous progenitor cells into ischemic tissue of patients is
emerging as a novel therapeutic option. Here, we report the potential impact of cultured …

Autologous adipose-derived regenerative cells for therapeutic angiogenesis

T Murohara, S Shintani, K Kondo - Current pharmaceutical …, 2009 - ingentaconnect.com
Therapeutic angiogenesis is an important means to salvage tissues against severe ischemic
diseases in patients with no option for other vascular intervention. A number of recent …

Unsorted human adipose tissue-derived stem cells promote angiogenesis and myogenesis in murine ischemic hindlimb model

Y Kang, C Park, D Kim, CM Seong, K Kwon… - Microvascular …, 2010 - Elsevier
We examined the protective effect of unsorted human adipose tissue-derived stem cells
(hADSCs) with a short-term culture in endothelial differentiation medium on tissue repair …

Therapeutic angiogenesis of adipose-derived stem cells for ischemic diseases

L Zhao, T Johnson, D Liu - Stem cell research & therapy, 2017 - Springer
Ischemic diseases, the leading cause of disability and death, are caused by the stenosis or
obstruction of arterioles/capillaries that is not compensated for by vessel dilatation or …

Angiogenesis in ischemic tissue produced by spheroid grafting of human adipose-derived stromal cells

SH Bhang, SW Cho, WG La, TJ Lee, HS Yang, AY Sun… - Biomaterials, 2011 - Elsevier
Stem cells offer significant therapeutic promise for the treatment of ischemic disease.
However, stem cells transplanted into ischemic tissue exhibit limited therapeutic efficacy due …