Population pharmacokinetics and pharmacodynamics of piperacillin and tazobactam administered by prolonged infusion in obese and nonobese patients
EK Chung, SC Cheatham, MR Fleming… - The Journal of …, 2015 - Wiley Online Library
The study objective was to evaluate the population pharmacokinetics and
pharmacodynamics of piperacillin and tazobactam administered by prolonged infusion in …
pharmacodynamics of piperacillin and tazobactam administered by prolonged infusion in …
Steady-state pharmacokinetics and pharmacodynamics of piperacillin and tazobactam administered by prolonged infusion in obese patients
SC Cheatham, MR Fleming, DP Healy… - International journal of …, 2013 - Elsevier
The study objective was to evaluate steady-state pharmacokinetics and pharmacodynamics
of piperacillin and tazobactam administered by prolonged infusion in obese patients …
of piperacillin and tazobactam administered by prolonged infusion in obese patients …
Serum piperacillin/tazobactam pharmacokinetics in a morbidly obese individual
D Newman, MH Scheetz, OA Adeyemi… - Annals of …, 2007 - journals.sagepub.com
Objective: To report pharmacokinetic alterations and optimal dosing of piperacillin/
tazobactam in an obese patient. Case Summary: A 39-year-old morbidly obese (weight 167 …
tazobactam in an obese patient. Case Summary: A 39-year-old morbidly obese (weight 167 …
Pharmacokinetic analysis of piperacillin administered with tazobactam in critically ill, morbidly obese surgical patients
AW Sturm, N Allen, KD Rafferty, DN Fish… - … : The Journal of …, 2014 - Wiley Online Library
Study Objective To evaluate the steady‐state pharmacokinetic and pharmacodynamic
parameters of piperacillin in morbidly obese, surgical intensive care patients. Design Open …
parameters of piperacillin in morbidly obese, surgical intensive care patients. Design Open …
Population pharmacokinetics of piperacillin in nonobese, obese, and morbidly obese critically ill patients
The treatment of infections in critically ill obese and morbidly obese patients is challenging
because of the combined physiological changes that result from obesity and critical illness …
because of the combined physiological changes that result from obesity and critical illness …
Population pharmacokinetics and pharmacodynamics of extended-infusion piperacillin and tazobactam in critically ill children
K Nichols, EK Chung, CA Knoderer… - Antimicrobial agents …, 2016 - Am Soc Microbiol
The study objective was to evaluate the population pharmacokinetics and
pharmacodynamics of extended-infusion piperacillin-tazobactam in children hospitalized in …
pharmacodynamics of extended-infusion piperacillin-tazobactam in children hospitalized in …
Piperacillin-tazobactam in intensive care units: a review of population pharmacokinetic analyses
I El-Haffaf, JA Caissy, A Marsot - Clinical pharmacokinetics, 2021 - Springer
Piperacillin-tazobactam is a potent β-lactam/β-lactamase inhibitor antibiotic commonly
prescribed in the intensive care unit setting. Admitted patients often show large variability in …
prescribed in the intensive care unit setting. Admitted patients often show large variability in …
Repeated Piperacillin-Tazobactam Plasma Concentration Measurements in Severely Obese Versus Nonobese Critically Ill Septic Patients and the Risk of Under–and …
Objective: Obesity and critical illness modify pharmacokinetics of antibiotics, but piperacillin-
tazobactam continuous IV infusion pharmacokinetics has been poorly studied in obese …
tazobactam continuous IV infusion pharmacokinetics has been poorly studied in obese …
Population pharmacokinetics of piperacillin at two dose levels: influence of nonlinear pharmacokinetics on the pharmacodynamic profile
CB Landersdorfer, JB Bulitta… - Antimicrobial agents …, 2012 - Am Soc Microbiol
Piperacillin in combination with tazobactam is one of the most commonly used intravenous
antibiotics. There is evidence for a possible saturable elimination of piperacillin. Therefore …
antibiotics. There is evidence for a possible saturable elimination of piperacillin. Therefore …
Population pharmacokinetics of extended-infusion piperacillin-tazobactam in hospitalized patients with nosocomial infections
While extended infusions of piperacillin-tazobactam (TZP) are increasingly used in practice,
the effect of infusion on the pharmacokinetic (PK) profile of TZP has not been widely …
the effect of infusion on the pharmacokinetic (PK) profile of TZP has not been widely …