Anorexia Nervosa (AN) is viewed as primarily a psychiatric disorder owing to the
considerable behavioral and genetic overlap with mood disorders and other psychiatric …

The hormone ghrelin stimulates eating and helps maintain blood glucose upon caloric
restriction. While previous studies have demonstrated that hypothalamic arcuate AgRP …

Anorexia Nervosa (AN) is a complex disease that impairs the metabolic, mental and
physiological health of affected individuals in a severe and sometimes lethal way. Many of …

Objective The sensory detection of food and food cues suppresses Agouti related peptide
(AgRP) neuronal activity prior to consumption with greatest suppression occurring in …

Increasing clinical and therapeutic interest in the neurobiology of eating disorders reflects
their dramatic impact on health. Chronic food restriction resulting in severe weight loss is a …

Ghrelin is a stomach hormone, secreted into the bloodstream, that initiates food intake by
activating NPY/AgRP neurons in the hypothalamic acruate nucleus. This review focuses on …

Ghrelin is a gut hormone that signals to the hypothalamus to stimulate growth hormone
release, increase food intake and promote fat deposition. The ghrelin receptor, also known …

Ghrelin plays an important role in energy metabolism by regulating food intake, body weight
and glucose homeostasis. In this review, we highlight recent developments describing how …

Ghrelin is upregulated under negative energy balance conditions, including starvation and
hypoglycemia, while it is downregulated under situations of positive energy balance, such …

Evidence contributing to the understanding of neurobiological mechanisms underlying
appetite dysregulation in anorexia nervosa draws heavily on separate lines of research into …