CCSVI and MS: no meaning, no fact

C Baracchini, M Atzori, P Gallo - Neurological Sciences, 2013 - Springer
A condition called “chronic cerebrospinal venous insufficiency”(CCSVI) has been postulated
to play a role in the pathogenesis of multiple sclerosis (MS). This hypothesis implies that a …

[HTML][HTML] Chronic cerebrospinal venous insufficiency in multiple sclerosis: a historical perspective

MD Dake, R Zivadinov, EM Haacke - Functional neurology, 2011 - ncbi.nlm.nih.gov
Chronic cerebrospinal venous insufficiency (CCSVI) is a term used to describe impaired
venous drainage from the central nervous system (CNS) caused by abnormalities in …

CCSVI is associated with multiple sclerosis

S Morovic, P Zamboni - Neurological research, 2012 - Taylor & Francis
Objectives: To analyze all the arguments against chronic cerebrospinal venous insufficiency
(CCSVI) as a medical entity, and its association with multiple sclerosis (MS) and to revise all …

Cerebrospinal venous insufficiency and multiple sclerosis: investigating the truth

O Khan - Multiple Sclerosis Journal, 2011 - journals.sagepub.com
The hypothesis that extra-cranial venous flow abnormalities leading to a stagnant venous
return contribute to the pathogenesis of multiple sclerosis (MS) has generated passionate …

CCSVI deconstructed and discarded

F Barkhof, MP Wattjes - Nature Reviews Neurology, 2013 - nature.com
Chronic cerebrospinal venous insufficiency (CCSVI) has been proposed as a cause of
multiple sclerosis (MS). However, two new studies found a very low overall prevalence of …

Neurosonological evaluation of cerebral venous outflow

G Malferrari, M Zedde, P Prati - Italia: Springer-Verlag, 2014 - Springer
Although the physiological mechanisms associated with cerebral-venous outflow are poorly
understood, abnormalities of the venous system have been implicated in a variety of …

Chronic cerebro-spinal venous insufficiency (CCSVI) and multiple sclerosis

A Ghezzi, G Comi, A Federico - Neurological Sciences, 2011 - Springer
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the CNS caused by the
interplay of genetic and environmental factors. In the last years, it has been suggested that …

" Chronic cerebrospinal venous insufficiency" in multiple sclerosis-is multiple sclerosis a disease of the cerebrospinal venous outflow system?

MP Wattjes, F Doepp, M Bendszus… - Rofo: Fortschritte auf dem …, 2011 - europepmc.org
Chronic impaired venous outflow from the central nervous system has recently been claimed
to be associated with multiple sclerosis (MS) pathology. This resulted in the term chronic …

[HTML][HTML] Evidence against the involvement of chronic cerebrospinal venous abnormalities in multiple sclerosis. A case-control study

IW Rodger, D Dilar, J Dwyer, J Bienenstock, A Coret… - PLoS …, 2013 - journals.plos.org
Objective Multiple sclerosis (MS) is a chronic neurodegenerative disease of the CNS.
Recently a controversial vascular hypothesis for MS, termed chronic cerebrospinal venous …

Progressive multiple sclerosis is not associated with chronic cerebrospinal venous insufficiency

C Baracchini, P Perini, F Causin, M Calabrese… - Neurology, 2011 - AAN Enterprises
Objective: Chronic cerebrospinal venous insufficiency (CCSVI) had been suggested to play
a major pathogenetic role in multiple sclerosis (MS), but recent data on early stages of MS …