EXPRESSION of genes coding for ubiquitin and heatshock protein (hsp) 70 were examined
by in situ hybridization using a rat model with permanent occlusion of the distal middle …

Ubiquitin gene expression following transient forebrain ischemia in the rat was analyzed by
three probes which were specific for UbC, UbB and UbS30 mRNA. According to the in situ …

Ubiquitin (Ub) is a small 76-residue protein, involved in intracellular protein degradation
through a specific ATP-dependent system, which uses Ub as a tag to label proteins …

Heat shock proteins (HSP) have been highly conserved throughout evolution and are
considered to have constitutive functions in protein synthesis as well as protection of cell in …

The purpose of the present study is to determine the effect of mild hypothermia on the
synthesis of ubiquitin, an important protein for maintenance of cell viability, in the …

The hippocampus is a brain structure specifically vulnerable to short periods of transient
cerebral ischemia, and which displays delayed neuronal necrosis. Protein ubiquitination is a …

A number of studies have demonstrated increased synthesis of heat shock proteins in brain
following hyperthermia or transient ischemia. In the present experiments we have …

The aim of this study was to investigate the effect of transient global brain ischaemia, both
naïve and preconditioned, on accumulation of ubiquitinylated proteins and induction of …

Cerebrd ischemia is a major cause of disability and death in the United States with over
500,000 cases annually. Two general kinds of cerebral ischemia are identified-focal and …

Using immunohistochemistry, we visualized the localization of ubiquitin in the gerbil
hippocampus following 3 min of ischemia with or without pretreatment with 2 min of …