Difference in triptan effect in patients with migraine and early allodynia

C Lampi, G Huber, S Haas, E Rittberger… - …, 2008 - journals.sagepub.com
The aim of this study was to determine whether in migraine patients with and without aura
early treatment with various triptans leads to differences in pain reduction after 1 h and in …

Sumatriptan 6 mg subcutaneous as an effective migraine treatment in patients with cutaneous allodynia who historically fail to respond to oral triptans

S Diamond, FG Freitag, A Feoktistov… - The Journal of headache …, 2007 - Springer
The objective of the study was to assess the efficacy of 6 mg subcutaneous (SC) sumatriptan
to treat migraine and the relationship between response of migraine and cutaneous …

Revisiting the efficacy of sumatriptan therapy during the aura phase of migraine

SK Aurora, PM Barrodale, SA McDonald… - … : The Journal of …, 2009 - Wiley Online Library
Objective.—To reexamine the efficacy of terminating migraine headache by administration of
sumatriptan during the visual‐aura phase of the attack. Background.—Although the …

Early responses in randomized clinical trials of triptans in acute migraine treatment. Are they clinically relevant? A comment

P Tfelt‐Hansen - Headache: The Journal of Head and Face …, 2010 - Wiley Online Library
(Headache 2010; 50: 1198‐1200) One can question the clinical relevance of early
headache responses after oral and intranasal triptans. Thus, for pain‐free the early …

Maximum effect of triptans in migraine? A comment

P Tfelt-Hansen - Cephalalgia, 2008 - journals.sagepub.com
The efficacy of triptans in the treatment of migraine was recently contested. How high is then
the maximum effect of a triptan? After subcutaneous naratriptan 10 mg a 88% pain-free …

Almotriptan and its combination with aceclofenac for migraine attacks: a study of efficacy and the influence of auto-evaluated brush allodynia

J Schoenen, ND Klippel, S Giurgea… - …, 2008 - journals.sagepub.com
Early treatment and combining a triptan with a non-steroidal anti-inflammatory drug (NSAID)
are thought to improve outcome during migraine attacks, possibly by counteracting the …

Cutaneous allodynia and migraine: another view

C Dahlöf - Current Pain and Headache Reports, 2006 - Springer
The paradigm of early treatment of the migraine attack at mild pain intensity has become one
alternative to circumventing the problem of compromised oral absorption of symptomatic …

Clarification of developing and established clinical allodynia and pain‐free outcomes

SH Landy, JE McGinnis… - Headache: The Journal …, 2007 - Wiley Online Library
Objective.—The aim of this study was to determine whether clinical indicators of cutaneous
allodynia predict the success of migraine therapy with sumatriptan using a brief …

Clinical benefits of early triptan therapy for migraine

J Pascual - Headache: The Journal of Head and Face Pain, 2002 - Wiley Online Library
Although triptans have been proven effective for acute treatment of migraine, reserving them
for moderate or severe pain may produce suboptimal pain relief and higher rates of …

Sumatriptan–naproxen migraine efficacy in allodynic patients: Early intervention

S Landy, R Hoagland… - Headache: The Journal of …, 2012 - Wiley Online Library
Objective.—This study evaluated the effectiveness of a single fixed‐dose tablet of
sumatriptan 85 mg/naproxen sodium 500 mg (sumatriptan–naproxen) using a very early …