Cardiopoietic stem cell therapy in heart failure: the C-CURE (Cardiopoietic stem Cell therapy in heart failURE) multicenter randomized trial with lineage-specified …
J Bartunek, A Behfar, D Dolatabadi… - Journal of the American …, 2013 - jacc.org
Objectives: This study sought to evaluate the feasibility and safety of autologous bone
marrow–derived and cardiogenically oriented mesenchymal stem cell therapy and to probe …
marrow–derived and cardiogenically oriented mesenchymal stem cell therapy and to probe …
Cardiopoietic cell therapy for advanced ischaemic heart failure: results at 39 weeks of the prospective, randomized, double blind, sham-controlled CHART-1 clinical …
J Bartunek, A Terzic, BA Davison… - European heart …, 2017 - academic.oup.com
Aims Cardiopoietic cells, produced through cardiogenic conditioning of patients'
mesenchymal stem cells, have shown preliminary efficacy. The Congestive Heart Failure …
mesenchymal stem cells, have shown preliminary efficacy. The Congestive Heart Failure …
Congestive heart failure cardiopoietic regenerative therapy (CHART‐1) trial design
J Bartunek, B Davison, W Sherman… - European journal of …, 2016 - Wiley Online Library
Aims Cardiopoiesis is a conditioning programme that aims to upgrade the
cardioregenerative aptitude of patient‐derived stem cells through lineage specification …
cardioregenerative aptitude of patient‐derived stem cells through lineage specification …
Dose comparison study of allogeneic mesenchymal stem cells in patients with ischemic cardiomyopathy (the TRIDENT study)
V Florea, AC Rieger, DL DiFede… - Circulation …, 2017 - Am Heart Assoc
Rationale: Cell dose and concentration play crucial roles in phenotypic responses to cell-
based therapy for heart failure. Objective: To compare the safety and efficacy of 2 doses of …
based therapy for heart failure. Objective: To compare the safety and efficacy of 2 doses of …
The advancing field of cell‐based therapy: insights and lessons from clinical trials
KS Telukuntla, VY Suncion, IH Schulman… - Journal of the …, 2013 - Am Heart Assoc
Stem cell therapy aimed at restoring organ function, notably myocardial repair and
regeneration postmyocardial infarction (MI), is one of the most exciting and promising …
regeneration postmyocardial infarction (MI), is one of the most exciting and promising …
Adult stem cell therapy and heart failure, 2000 to 2016: a systematic review
Importance Stem cell therapy is a promising treatment strategy for patients with heart failure,
which accounts for more than 10% of deaths in the United States annually. Despite more …
which accounts for more than 10% of deaths in the United States annually. Despite more …
Cardiac cell therapy: lessons from clinical trials
P Menasche - Journal of molecular and cellular cardiology, 2011 - Elsevier
Cardiac cell therapy has now been in clinical use since 10years. Both autologous skeletal
myoblasts and bone marrow-derived different cell subsets (mononuclear cells …
myoblasts and bone marrow-derived different cell subsets (mononuclear cells …
Rationale and Design of the CONCERT-HF Trial (Combination of Mesenchymal and c-kit+ Cardiac Stem Cells As Regenerative Therapy for Heart Failure)
Rationale: Autologous bone marrow mesenchymal stem cells (MSCs) and c-kit+ cardiac
progenitor cells (CPCs) are 2 promising cell types being evaluated for patients with heart …
progenitor cells (CPCs) are 2 promising cell types being evaluated for patients with heart …
Benefit of cardiopoietic mesenchymal stem cell therapy on left ventricular remodelling: results from the Congestive Heart Failure Cardiopoietic Regenerative Therapy …
Aims Left ventricular (LV) reverse remodelling is an important marker of improved outcomes
in patients with advanced heart failure (HF). We examined the impact of the intramyocardial …
in patients with advanced heart failure (HF). We examined the impact of the intramyocardial …
Cell therapy in patients with heart failure: a comprehensive review and emerging concepts
R Bolli, M Solankhi, XL Tang… - Cardiovascular research, 2022 - academic.oup.com
This review summarizes the results of clinical trials of cell therapy in patients with heart
failure (HF). In contrast to acute myocardial infarction (where results have been consistently …
failure (HF). In contrast to acute myocardial infarction (where results have been consistently …
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