TolC-dependent modulation of host cell death by the Francisella tularensis live vaccine strain
Francisella tularensis is a facultative intracellular, Gram-negative pathogen and the
causative agent of tularemia. We previously identified TolC as a virulence factor of the F …
causative agent of tularemia. We previously identified TolC as a virulence factor of the F …
A tolC Mutant of Francisella tularensis Is Hypercytotoxic Compared to the Wild Type and Elicits Increased Proinflammatory Responses from Host Cells
GJ Platz, DAC Bublitz, P Mena, JL Benach… - Infection and …, 2010 - Am Soc Microbiol
The highly infectious bacterium Francisella tularensis is a facultative intracellular pathogen
and the causative agent of tularemia. TolC, which is an outer membrane protein involved in …
and the causative agent of tularemia. TolC, which is an outer membrane protein involved in …
Francisella tularensis disrupts TLR2-MYD88-p38 signaling early during infection to delay apoptosis of macrophages and promote virulence in the host
PT Benziger, EJ Kopping, PA McLaughlin… - Mbio, 2023 - Am Soc Microbiol
Francisella tularensis is a zoonotic pathogen and the causative agent of tularemia. F.
tularensis replicates to high levels within the cytosol of macrophages and other host cells …
tularensis replicates to high levels within the cytosol of macrophages and other host cells …
Deletion of TolC orthologs in Francisella tularensis identifies roles in multidrug resistance and virulence
H Gil, GJ Platz, CA Forestal, M Monfett… - Proceedings of the …, 2006 - National Acad Sciences
The Gram-negative bacterium Francisella tularensis is the causative agent of tularemia.
Interest in this zoonotic pathogen has increased due to its classification as a category A …
Interest in this zoonotic pathogen has increased due to its classification as a category A …
[HTML][HTML] From the Outside-In: The Francisella tularensis Envelope and Virulence
HM Rowe, JF Huntley - Frontiers in cellular and infection microbiology, 2015 - frontiersin.org
Francisella tularensis is a highly-infectious bacterium that causes the rapid, and often lethal
disease, tularemia. Many studies have been performed to identify and characterize the …
disease, tularemia. Many studies have been performed to identify and characterize the …
Innate immune response to Francisella tularensis is mediated by TLR2 and caspase-1 activation
H Li, S Nookala, XR Bina, JE Bina… - Journal of leukocyte …, 2006 - academic.oup.com
Francisella tularensis, a gram-negative, facultative, intracellular bacterium, is the etiologic
agent of tularemia and a category A bioterrorism agent. Little is known about the mechanism …
agent of tularemia and a category A bioterrorism agent. Little is known about the mechanism …
[HTML][HTML] TLR–Dependent Control of Francisella tularensis Infection and Host Inflammatory Responses
Background Francisella tularensis is the causative agent of tularemia and is classified as a
Category A select agent. Recent studies have implicated TLR2 as a critical element in the …
Category A select agent. Recent studies have implicated TLR2 as a critical element in the …
Toll-Like Receptor 2-Mediated Signaling Requirements for Francisella tularensis Live Vaccine Strain Infection of Murine Macrophages
LE Cole, KA Shirey, E Barry, A Santiago… - Infection and …, 2007 - Am Soc Microbiol
Francisella tularensis, an aerobic, non-spore-forming, gram-negative coccobacillus, is the
causative agent of tularemia. We reported previously that F. tularensis live vaccine strain …
causative agent of tularemia. We reported previously that F. tularensis live vaccine strain …
Francisella tularensis live vaccine strain induces macrophage alternative activation as a survival mechanism
KA Shirey, LE Cole, AD Keegan… - The Journal of …, 2008 - journals.aai.org
Francisella tularensis (Ft), the causative agent of tularemia, elicits a potent inflammatory
response early in infection, yet persists within host macrophages and can be lethal if left …
response early in infection, yet persists within host macrophages and can be lethal if left …
Contributions of TolC Orthologs to Francisella tularensis Schu S4 Multidrug Resistance, Modulation of Host Cell Responses, and Virulence
EJ Kopping, CR Doyle, V Sampath… - Infection and …, 2019 - Am Soc Microbiol
Francisella tularensis is a Gram-negative, facultative intracellular pathogen and the
causative agent of tularemia. Previous studies with the attenuated live vaccine strain (LVS) …
causative agent of tularemia. Previous studies with the attenuated live vaccine strain (LVS) …