Background Patients with newly diagnosed non-metastatic prostate adenocarcinoma are
typically classified as at low, intermediate, or high risk of disease progression using blood …

(1) Background: One of the most common cancers that affect North American men and men
worldwide is prostate cancer. The Gleason score is a pathological grading system to …

Background: Prostate cancer is a significant clinical issue, particularly for high Gleason
score (GS) malignancy patients. Our study aimed to engineer and validate a risk model …

Prostate cancer is one of the most common types of cancer among Canadian men. Next-
generation sequencing using RNA-Seq provides large amounts of data that may reveal …

Predicting prognosis in prostate carcinoma remains a challenge when using clinical and
pathologic criteria only. We used an array-based DASL® assay to identify molecular …

High Gleason score is currently the best prognostic indicator for poor prognosis in prostate
cancer. However, a significant number of patients with low Gleason scores develop …

Background: Compared to non-recurrent type, recurrent prostate adenocarcinoma (PCa) is
highly fatal, and significantly shortens the survival time of affected patients. Early and …

Determining which treatment to provide to men with prostate cancer (PCa) is a major
challenge for clinicians. Currently, the clinical risk-stratification for PCa is based on clinico …

Background Prostate adenocarcinoma (PRAD) is a common cancer diagnosis among men
globally, yet large gaps in our knowledge persist with respect to the molecular bases of its …

Overtreatment remains a pervasive problem in prostate cancer management due to the
highly variable and often indolent course of disease. Molecular signatures derived from …