Working toward the Future: Insights into Francisella tularensis Pathogenesis and Vaccine Development
RD Pechous, TR McCarthy… - … and molecular biology …, 2009 - Am Soc Microbiol
Francisella tularensis is a facultative intracellular gram-negative pathogen and the
etiological agent of the zoonotic disease tularemia. Recent advances in the field of …
etiological agent of the zoonotic disease tularemia. Recent advances in the field of …
Molecular and Genetic Basis of Pathogenesis in Francisella Tularensis
The genetic means of pathogenesis of Francisella tularensis are poorly understood. F.
tularensis is able to survive and replicate within macrophages, and a virulence factor, MglA …
tularensis is able to survive and replicate within macrophages, and a virulence factor, MglA …
Mechanisms of Francisella tularensis intracellular pathogenesis
J Celli, TC Zahrt - Cold Spring Harbor …, 2013 - perspectivesinmedicine.cshlp.org
Francisella tularensis is a zoonotic intracellular pathogen and the causative agent of the
debilitating febrile illness tularemia. Although natural infections by F. tularensis are sporadic …
debilitating febrile illness tularemia. Although natural infections by F. tularensis are sporadic …
The unraveling panoply of Francisella tularensis virulence attributes
KL Meibom, A Charbit - Current opinion in microbiology, 2010 - Elsevier
Francisella tularensis is a highly infectious Gram-negative bacterium causing the zoonotic
disease tularemia. This facultative intracellular pathogen multiplies in vivo mainly inside …
disease tularemia. This facultative intracellular pathogen multiplies in vivo mainly inside …
Francisella tularensis: unravelling the secrets of an intracellular pathogen
PCF Oyston - Journal of medical microbiology, 2008 - microbiologyresearch.org
Francisella tularensis has been recognized as the causative agent of tularaemia for almost a
century. Since its discovery in 1911, it has been shown to infect a wide range of hosts …
century. Since its discovery in 1911, it has been shown to infect a wide range of hosts …
Virulence determinants and protective antigens of Francisella tularensis
A Sjöstedt - Current opinion in microbiology, 2003 - Elsevier
Very little is known about virulence mechanisms of the highly virulent bacterium Francisella
tularensis. Specific genetic features of F. tularensis have been obstacles for the …
tularensis. Specific genetic features of F. tularensis have been obstacles for the …
A Francisella tularensis Pathogenicity Island Required for Intramacrophage Growth
Francisella tularensis is a gram-negative, facultative intracellular pathogen that causes the
highly infectious zoonotic disease tularemia. We have discovered a ca. 30-kb pathogenicity …
highly infectious zoonotic disease tularemia. We have discovered a ca. 30-kb pathogenicity …
Attenuated Francisella novicida Transposon Mutants Protect Mice against Wild-Type Challenge
R Tempel, XH Lai, L Crosa, B Kozlowicz… - Infection and …, 2006 - Am Soc Microbiol
Francisella tularensis is the bacterial pathogen that causes tularemia in humans and a
number of animals. To date, there is no approved vaccine for this widespread and life …
number of animals. To date, there is no approved vaccine for this widespread and life …
Directed Screen of Francisella novicida Virulence Determinants Using Drosophila melanogaster
MK Åhlund, P Rydén, A Sjöstedt… - Infection and …, 2010 - Am Soc Microbiol
Francisella tularensis is a highly virulent, facultative intracellular human pathogen whose
virulence mechanisms are not well understood. Occasional outbreaks of tularemia and the …
virulence mechanisms are not well understood. Occasional outbreaks of tularemia and the …
Will the enigma of Francisella tularensis virulence soon be solved?
Francisella tularensis is one of the most infectious bacterial pathogens known and is the
causative agent of the zoonotic disease tularemia. In spite of the importance of this pathogen …
causative agent of the zoonotic disease tularemia. In spite of the importance of this pathogen …