The tumour microenvironment and tumour angiogenesis play a critical role in the
development and therapy of many cancers, but in vitro models reflecting these …

Angiogenesis marks the transformation of a benign local tumor into a life‐threatening
disease. Many in vitro assays are available on two‐dimensional (2D) platforms, however …

The induction of angiogenesis and the promotion of tumor growth and invasiveness are
processes critical to metastasis, and are dependent on reciprocal interactions between …

Angiogenesis is now well known for being involved in tumor progression, aggressiveness,
emergence of metastases, and also resistance to cancer therapies. In this study, to better …

We present a 3D multi-cell simulation of a generic simplification of vascular tumor growth
which can be easily extended and adapted to describe more specific vascular tumor types …

Tumor angiogenesis is critical to tumor growth and metastasis, yet much is unknown about
the role vascular cells play in the tumor microenvironment. In vitro models that mimic in vivo …

The hallmark of tumours is the ability of cancerous cells to promote vascular growth, to
disseminate and invade to distant organs. The metastatic process is heavily influenced by …

Objectives The high levels of morbidity and mortality associated with cancer can be
attributed to two main processes; the tumour's ability to rapidly proliferate and the process of …

Angiogenesis is indispensable for solid tumor expansion, and thus it has become a major
target of cancer research and anti-cancer therapies. Deciphering the arcane actions of …

The development of blood vessels, referred to as angiogenesis, is an intricate process
regulated spatially and temporally through a delicate balance between the qualitative and …