[HTML][HTML] Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations
Alcohol consumption level and alcohol use disorder (AUD) diagnosis are moderately
heritable traits. We conduct genome-wide association studies of these traits using …
heritable traits. We conduct genome-wide association studies of these traits using …
Item-level genome-wide association study of the alcohol use disorders identification test in three population-based cohorts
Objective: Genome-wide association studies (GWASs) of the Alcohol Use Disorders
Identification Test (AUDIT), a 10-item screen for alcohol use disorder (AUD), have elucidated …
Identification Test (AUDIT), a 10-item screen for alcohol use disorder (AUD), have elucidated …
Genome‐wide association study of alcohol use disorder identification test (AUDIT) scores in 20 328 research participants of European ancestry
S Sanchez‐Roige, P Fontanillas, SL Elson… - Addiction …, 2019 - Wiley Online Library
Genetic factors contribute to the risk for developing alcohol use disorder (AUD). In
collaboration with the genetics company 23andMe, Inc., we performed a genome‐wide …
collaboration with the genetics company 23andMe, Inc., we performed a genome‐wide …
Genetics of alcohol use disorder: a review
Alcohol use disorder (AUD) represents a significant and ongoing public health concern with
12-month prevalence estimates of∼ 5.6%. Quantitative genetic studies suggest a heritability …
12-month prevalence estimates of∼ 5.6%. Quantitative genetic studies suggest a heritability …
Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study
E Jorgenson, KK Thai, TJ Hoffmann, LC Sakoda… - Molecular …, 2017 - nature.com
Alcohol consumption is a complex trait determined by both genetic and environmental
factors, and is correlated with the risk of alcohol use disorders. Although a small number of …
factors, and is correlated with the risk of alcohol use disorders. Although a small number of …
Alcohol dependence genetics: lessons learned from genome‐wide association studies (GWAS) and post‐GWAS analyses
AB Hart, HR Kranzler - Alcoholism: clinical and experimental …, 2015 - Wiley Online Library
Background Alcohol dependence (AD) is a complex psychiatric disorder and a significant
public health problem. Twin and family‐based studies have consistently estimated its …
public health problem. Twin and family‐based studies have consistently estimated its …
Genome-wide association study meta-analysis of the alcohol use disorders identification test (AUDIT) in two population-based cohorts
S Sanchez-Roige, AA Palmer… - American Journal of …, 2019 - Am Psychiatric Assoc
Objective: Alcohol use disorders are common conditions that have enormous social and
economic consequences. Genome-wide association analyses were performed to identify …
economic consequences. Genome-wide association analyses were performed to identify …
Overview of the genetics of alcohol use disorder
EA Tawa, SD Hall, FW Lohoff - Alcohol and alcoholism, 2016 - academic.oup.com
Abstract Aims Alcohol Use Disorder (AUD) is a chronic psychiatric illness characterized by
harmful drinking patterns leading to negative emotional, physical, and social ramifications …
harmful drinking patterns leading to negative emotional, physical, and social ramifications …
Genome‐wide association studies of alcohol dependence, DSM‐IV criterion count and individual criteria
Genome‐wide association studies (GWAS) of alcohol dependence (AD) have reliably
identified variation within alcohol metabolizing genes (eg, ADH1B) but have inconsistently …
identified variation within alcohol metabolizing genes (eg, ADH1B) but have inconsistently …
A genome-wide association study of alcohol dependence
Excessive alcohol consumption is one of the leading causes of preventable death in the
United States. Approximately 14% of those who use alcohol meet criteria during their lifetime …
United States. Approximately 14% of those who use alcohol meet criteria during their lifetime …