[HTML][HTML] Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations

HR Kranzler, H Zhou, RL Kember… - Nature …, 2019 - nature.com
Alcohol consumption level and alcohol use disorder (AUD) diagnosis are moderately
heritable traits. We conduct genome-wide association studies of these traits using …

Item-level genome-wide association study of the alcohol use disorders identification test in three population-based cohorts

TT Mallard, JE Savage, EC Johnson… - American Journal of …, 2022 - Am Psychiatric Assoc
Objective: Genome-wide association studies (GWASs) of the Alcohol Use Disorders
Identification Test (AUDIT), a 10-item screen for alcohol use disorder (AUD), have elucidated …

Genome‐wide association study of alcohol use disorder identification test (AUDIT) scores in 20 328 research participants of European ancestry

S Sanchez‐Roige, P Fontanillas, SL Elson… - Addiction …, 2019 - Wiley Online Library
Genetic factors contribute to the risk for developing alcohol use disorder (AUD). In
collaboration with the genetics company 23andMe, Inc., we performed a genome‐wide …

Genetics of alcohol use disorder: a review

JD Deak, AP Miller, IR Gizer - Current opinion in psychology, 2019 - Elsevier
Alcohol use disorder (AUD) represents a significant and ongoing public health concern with
12-month prevalence estimates of∼ 5.6%. Quantitative genetic studies suggest a heritability …

Genetic contributors to variation in alcohol consumption vary by race/ethnicity in a large multi-ethnic genome-wide association study

E Jorgenson, KK Thai, TJ Hoffmann, LC Sakoda… - Molecular …, 2017 - nature.com
Alcohol consumption is a complex trait determined by both genetic and environmental
factors, and is correlated with the risk of alcohol use disorders. Although a small number of …

Alcohol dependence genetics: lessons learned from genome‐wide association studies (GWAS) and post‐GWAS analyses

AB Hart, HR Kranzler - Alcoholism: clinical and experimental …, 2015 - Wiley Online Library
Background Alcohol dependence (AD) is a complex psychiatric disorder and a significant
public health problem. Twin and family‐based studies have consistently estimated its …

Genome-wide association study meta-analysis of the alcohol use disorders identification test (AUDIT) in two population-based cohorts

S Sanchez-Roige, AA Palmer… - American Journal of …, 2019 - Am Psychiatric Assoc
Objective: Alcohol use disorders are common conditions that have enormous social and
economic consequences. Genome-wide association analyses were performed to identify …

Overview of the genetics of alcohol use disorder

EA Tawa, SD Hall, FW Lohoff - Alcohol and alcoholism, 2016 - academic.oup.com
Abstract Aims Alcohol Use Disorder (AUD) is a chronic psychiatric illness characterized by
harmful drinking patterns leading to negative emotional, physical, and social ramifications …

Genome‐wide association studies of alcohol dependence, DSM‐IV criterion count and individual criteria

D Lai, L Wetherill, S Bertelsen, CE Carey… - Genes, Brain and …, 2019 - Wiley Online Library
Genome‐wide association studies (GWAS) of alcohol dependence (AD) have reliably
identified variation within alcohol metabolizing genes (eg, ADH1B) but have inconsistently …

A genome-wide association study of alcohol dependence

LJ Bierut, A Agrawal, KK Bucholz… - Proceedings of the …, 2010 - National Acad Sciences
Excessive alcohol consumption is one of the leading causes of preventable death in the
United States. Approximately 14% of those who use alcohol meet criteria during their lifetime …