Erratum: A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling

D Li, X Chang, JJ Connolly, L Tian, Y Liu, EJ Bhoj… - Scientific reports, 2017 - nature.com
Erratum: A genome-wide association study of anorexia nervosa suggests a risk locus
implicated in dysregulated leptin signaling Page 1 1 SCIENTIFIC REPORTS | 7: 8379 | DOI:10.1038/s41598-017-06409-3 …

[HTML][HTML] A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling

D Li, X Chang, JJ Connolly, L Tian, Y Liu, EJ Bhoj… - Scientific reports, 2017 - nature.com
We conducted a genome-wide association study (GWAS) of anorexia nervosa (AN) using a
stringently defined phenotype. Analysis of phenotypic variability led to the identification of a …

[HTML][HTML] Suggestive evidence for causal effect of leptin levels on risk for anorexia nervosa: Results of a mendelian randomization study

T Peters, J Antel, R Naaresh, BH Laabs… - Frontiers in …, 2021 - frontiersin.org
Genetic correlations suggest a coexisting genetic predisposition to both low leptin levels and
risk for anorexia nervosa (AN). To investigate the causality and direction of these …

Multiomic prioritisation of risk genes for anorexia nervosa

DM Adams, WR Reay, MJ Cairns - medRxiv, 2022 - medrxiv.org
Anorexia nervosa is the leading cause of mortality among psychiatric disorders worldwide.
Currently no medications are approved for anorexia nervosa treatment, and thus …

[HTML][HTML] Association of leptin gene DNA methylation with diagnosis and treatment outcome of anorexia nervosa

A Neyazi, V Buchholz, A Burkert, T Hillemacher… - Frontiers in …, 2019 - frontiersin.org
Epigenetic alterations are increasingly implicated in the pathophysiology of anorexia
nervosa (AN) but are as yet poorly understood. We investigated possible associations …

[HTML][HTML] Genome-wide association study reveals first locus for anorexia nervosa and metabolic correlations

L Duncan, Z Yilmaz, R Walters, J Goldstein… - The American journal …, 2017 - ncbi.nlm.nih.gov
Objective To conduct a genome-wide association study (GWAS) of anorexia nervosa and to
calculate genetic correlations with a series of psychiatric, educational, and metabolic …

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

HJ Watson, Z Yilmaz, LM Thornton, C Hübel… - Nature …, 2019 - nature.com
Characterized primarily by a low body-mass index, anorexia nervosa is a complex and
serious illness, affecting 0.9–4% of women and 0.3% of men,–, with twin-based heritability …

[HTML][HTML] Molecular neuroanatomy of anorexia nervosa

D Howard, P Negraes, AN Voineskos, AS Kaplan… - Scientific reports, 2020 - nature.com
Anorexia nervosa is a complex eating disorder with genetic, metabolic, and psychosocial
underpinnings. Using genome-wide methods, recent studies have associated many genes …

Genetic contributions to the etiology of anorexia nervosa: New perspectives in molecular diagnosis and treatment

S Paolacci, AK Kiani, E Manara… - Molecular genetics & …, 2020 - Wiley Online Library
Background Anorexia nervosa is a multifactorial eating disorder that manifests with self‐
starvation, extreme anxiety, hyperactivity, and amenorrhea. Long‐term effects include organ …

Identifying tissues implicated in anorexia nervosa using transcriptomic imputation

LM Huckins, A Dobbyn, W McFadden, D Ruderfer… - bioRxiv, 2018 - biorxiv.org
Anorexia nervosa (AN) is a complex and serious eating disorder, occurring in~ 1% of
individuals. Despite having the highest mortality rate of any psychiatric disorder, little is …