Erratum: A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling
Erratum: A genome-wide association study of anorexia nervosa suggests a risk locus
implicated in dysregulated leptin signaling Page 1 1 SCIENTIFIC REPORTS | 7: 8379 | DOI:10.1038/s41598-017-06409-3 …
implicated in dysregulated leptin signaling Page 1 1 SCIENTIFIC REPORTS | 7: 8379 | DOI:10.1038/s41598-017-06409-3 …
[HTML][HTML] A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling
We conducted a genome-wide association study (GWAS) of anorexia nervosa (AN) using a
stringently defined phenotype. Analysis of phenotypic variability led to the identification of a …
stringently defined phenotype. Analysis of phenotypic variability led to the identification of a …
[HTML][HTML] Suggestive evidence for causal effect of leptin levels on risk for anorexia nervosa: Results of a mendelian randomization study
Genetic correlations suggest a coexisting genetic predisposition to both low leptin levels and
risk for anorexia nervosa (AN). To investigate the causality and direction of these …
risk for anorexia nervosa (AN). To investigate the causality and direction of these …
Multiomic prioritisation of risk genes for anorexia nervosa
Anorexia nervosa is the leading cause of mortality among psychiatric disorders worldwide.
Currently no medications are approved for anorexia nervosa treatment, and thus …
Currently no medications are approved for anorexia nervosa treatment, and thus …
[HTML][HTML] Association of leptin gene DNA methylation with diagnosis and treatment outcome of anorexia nervosa
A Neyazi, V Buchholz, A Burkert, T Hillemacher… - Frontiers in …, 2019 - frontiersin.org
Epigenetic alterations are increasingly implicated in the pathophysiology of anorexia
nervosa (AN) but are as yet poorly understood. We investigated possible associations …
nervosa (AN) but are as yet poorly understood. We investigated possible associations …
[HTML][HTML] Genome-wide association study reveals first locus for anorexia nervosa and metabolic correlations
L Duncan, Z Yilmaz, R Walters, J Goldstein… - The American journal …, 2017 - ncbi.nlm.nih.gov
Objective To conduct a genome-wide association study (GWAS) of anorexia nervosa and to
calculate genetic correlations with a series of psychiatric, educational, and metabolic …
calculate genetic correlations with a series of psychiatric, educational, and metabolic …
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
Characterized primarily by a low body-mass index, anorexia nervosa is a complex and
serious illness, affecting 0.9–4% of women and 0.3% of men,–, with twin-based heritability …
serious illness, affecting 0.9–4% of women and 0.3% of men,–, with twin-based heritability …
[HTML][HTML] Molecular neuroanatomy of anorexia nervosa
Anorexia nervosa is a complex eating disorder with genetic, metabolic, and psychosocial
underpinnings. Using genome-wide methods, recent studies have associated many genes …
underpinnings. Using genome-wide methods, recent studies have associated many genes …
Genetic contributions to the etiology of anorexia nervosa: New perspectives in molecular diagnosis and treatment
Background Anorexia nervosa is a multifactorial eating disorder that manifests with self‐
starvation, extreme anxiety, hyperactivity, and amenorrhea. Long‐term effects include organ …
starvation, extreme anxiety, hyperactivity, and amenorrhea. Long‐term effects include organ …
Identifying tissues implicated in anorexia nervosa using transcriptomic imputation
Anorexia nervosa (AN) is a complex and serious eating disorder, occurring in~ 1% of
individuals. Despite having the highest mortality rate of any psychiatric disorder, little is …
individuals. Despite having the highest mortality rate of any psychiatric disorder, little is …