Background Liver cirrhosis is an uncommon but not rare side effect of amiodarone-induced
hepatotoxicity. Patients with hepatitis B virus and hepatitis C virus infections are at a high …

Abstract Background/Aim The number of patients receiving amiodarone will increase in
future years. As clinically significant hepatotoxicity associated with oral amiodarone is …

Background: The prevalence of hepatotoxicity after longterm oral amiodarone therapy in
Chinese patients with or without elevated liver enzymes at baseline is unknown. Hypothesis …

Introduction. Amiodarone has been used for more than 5 decades for the treatment of
various tachyarrhythmias and previously for the treatment of refractory angina. There are …

Background: Amiodarone is associated with varying degrees of hepatotoxicity. Aims: to
study the association between the presence of the metabolic syndrome or rightsided heart …

Potential hepatotoxicity related to amiodarone therapy is often a concern when deciding
whether to initiate or continue treatment with this medication. While mostly associated with …

The anti-arrhythmic agent amiodarone (AD) is associated with numerous adverse effects,
but serious liver disease is rare. The improved safety of administration of daily low doses of …

The prevalence of apparent amiodarone-related hepatic injury in 104 patients followed
prospectively is compared to that reported in the literature. Asymptomatic elevation of serum …

Risk factors and underlying mechanisms for liver injury associated with amiodarone remain
elusive. This study aimed to investigate the drug-related covariates for acute liver injury by …

Background Amiodarone causes hepatotoxicity in experimental models, but in humans, the
relationships between drug administration, serum concentrations, markers of liver function …