[图书][B] Sophoraflavenone G is the major active compound of sophora flavecens against HCV replication

X Han - 2016 - search.proquest.com
Plant-derived compounds can provide an alternative approach to new medical therapies
with features including effectiveness, lower cost of production and milder side effects in …

Specific inhibition of hepatitis C virus entry into host hepatocytes by fungi-derived sulochrin and its derivatives

S Nakajima, K Watashi, S Kamisuki, S Tsukuda… - Biochemical and …, 2013 - Elsevier
Hepatitis C virus (HCV) is a major causative agent of hepatocellular carcinoma. Although
various classes of anti-HCV agents have been under clinical development, most of these …

Medicinal herbal extracts of Sophorae radix Acanthopanacis cortex Sanguisorbae radix and Torilis fructus inhibit coronavirus replication in vitro

HY Kim, EY Eo, H Park, YC Kim, S Park… - Antiviral …, 2010 - journals.sagepub.com
Background Cimicifuga rhizome Meliae cortex Coptidis rhizome and Phellodendron cortex
have been previously shown to exhibit anti-coronavirus activity. Here, an additional 19 …

[HTML][HTML] Sulforaphane suppresses hepatitis C virus replication by up-regulating heme oxygenase-1 expression through PI3K/Nrf2 pathway

JS Yu, WC Chen, CK Tseng, CK Lin, YC Hsu… - PloS one, 2016 - journals.plos.org
Hepatitis C virus (HCV) infection-induced oxidative stress is a major risk factor for the
development of HCV-associated liver disease. Sulforaphane (SFN) is an antioxidant …

[HTML][HTML] Lobohedleolide suppresses hepatitis C virus replication via JNK/c-Jun-C/EBP-mediated down-regulation of cyclooxygenase-2 expression

CK Lin, CK Tseng, CC Liaw, CY Huang, CK Wei… - Scientific reports, 2018 - nature.com
Hepatitis C virus (HCV) chronically infects 2–3% people of the global population, which
leads to liver cirrhosis and hepatocellular carcinoma. Drug resistance remains a serious …

Sulforaphane suppresses hepatitis C virus replication by up-regulating heme oxygenase-1 expression through PI3K/Nrf2 pathway.

YJS Yu JungSheng, CWC Chen WeiChun… - 2016 - cabidigitallibrary.org
Hepatitis C virus (HCV) infection-induced oxidative stress is a major risk factor for the
development of HCV-associated liver disease. Sulforaphane (SFN) is an antioxidant …

[HTML][HTML] Sophoraflavenone G restricts Dengue and Zika virus infection via RNA polymerase interference

A Sze, D Olagnier, S Bel Hadj, X Han, X Hong Tian… - Viruses, 2017 - mdpi.com
Flaviviruses including Zika, Dengue and Hepatitis C virus cause debilitating diseases in
humans, and the former are emerging as global health concerns with no antiviral treatments …

[HTML][HTML] Sophora interrupta Bedd. root-derived flavonoids as prominent antiviral agents against Newcastle disease virus

C Bhuvaneswar, A Rammohan, BV Bhaskar… - RSC …, 2020 - pubs.rsc.org
The discovery and development of novel antiviral drugs from natural sources is continuously
increasing due to limitations of currently available drugs such as toxic side effects, drug …

[HTML][HTML] Amentoflavone inhibits HSV-1 and ACV-resistant strain infection by suppressing viral early infection

F Li, X Song, G Su, Y Wang, Z Wang, J Jia, S Qing… - Viruses, 2019 - mdpi.com
Infection of Herpes simplex virus 1 (HSV-1) induces severe clinical disorders, such as
herpes simplex encephalitis and keratitis. Acyclovir (ACV) is the current therapeutic drug …

Active compounds from Saussurea lappa Clarks that suppress hepatitis B virus surface antigen gene expression in human hepatoma cells

HC Chen, CK Chou, SD Lee, JC Wang, SF Yeh - Antiviral Research, 1995 - Elsevier
We have examined the antiviral activity of the crude extract prepared from the root of
Saussurea lappa Clarks, a Chinese medicinal herb which is widely used for many illneses …