[HTML][HTML] Genetics of the Lp (a)/apo (a) system in an autochthonous Black African population from the Gabon

K Schmidt, HG Kraft, W Parson… - European journal of human …, 2006 - nature.com
Abstract Plasma lipoprotein (a)(Lp (a)) is a quantitative trait associated with atherothrombotic
disease in European and Asian populations. Lp (a) concentrations vary widely within and …

Genetic control of lipoprotein (a) concentrations is different in Africans and Caucasians

M Scholz, HG Kraft, A Lingenhel, R Delport… - European Journal of …, 1999 - nature.com
Abstract Lipoprotein (a)(Lp (a)) represents a quantitative trait in human plasma associated
with atherothrombotic disease. Large variation in the distribution of Lp (a) concentrations …

Significant impact of the+ 93 C/T polymorphism in the apolipoprotein (a) gene on Lp (a) concentrations in Africans but not in Caucasians: confounding effect of linkage …

HG Kraft, M Windegger, HJ Menzel… - Human molecular …, 1998 - academic.oup.com
Abstract Lipoprotein (a)[Lp (a)] is a quantitative genetic trait in human plasma associated
with atherothrombotic disease. The major determinant of Lp (a) concentration is the …

[PDF][PDF] The Apo (a) gene is the major determinant of variation in plasma Lp (a) levels in African Americans

V Mooser, D Scheer, SM Marcovina, J Wang… - The American Journal of …, 1997 - cell.com
The distributions of plasma lipoprotein (a), or Lp (a), levels differ significantly among ethnic
groups. Individuals of African descent have a two-to threefold higher mean plasma level of …

Relationship between plasma lipoprotein (a), apolipoprotein (a) phenotypes, and other coronary heart disease risk factors in a Melbourne South Asian population

ZW Xiong, ML Wahlqvist, TI Ibiebele, BM Biegler… - Clinical …, 2004 - Elsevier
Background: High plasma lipoprotein (a)[Lp (a)] level is a strong and important risk factor for
cardiovascular disease (CVD). Small-sized apolipoprotein (a)[apo (a)] isoforms (F, B, S1 …

Genetic architecture and evolution of the lipoprotein (a) trait

G Utermann - Current opinion in lipidology, 1999 - journals.lww.com
Apolipoprotein (a) is coded by one of the most polymorphic genes known in humans. In
white and Asian populations variation in this gene is the major determinant of the plasma …

Single nucleotide polymorphisms in exons of the apo (a) kringles IV types 6 to 10 domain affect Lp (a) plasma concentrations and have different patterns in Africans …

M Ogorelkova, HG Kraft, C Ehnholm… - Human molecular …, 2001 - academic.oup.com
Abstract Lipoprotein (a)[Lp (a)] is a complex of apolipoprotein (a)[apo (a)] and low-density
lipoprotein which is associated with atherothrombotic disease. Lp (a) plasma levels are …

The apolipoprotein (a) gene: linkage disequilibria at three loci differs in African Americans and Caucasians

J Rubin, HJ Kim, TA Pearson, S Holleran, L Berglund… - Atherosclerosis, 2008 - Elsevier
Lipoprotein (a)(Lp (a)) is an independent, genetically regulated cardiovascular risk factor. Lp
(a) plasma levels are largely determined by the apolipoprotein (a)(apo (a)) component, and …

Genetic factors explain a major fraction of the 50% lower lipoprotein (a) concentrations in Finns

G Erhart, C Lamina, T Lehtimäki… - … , and vascular biology, 2018 - Am Heart Assoc
Objective—Lp (a)(lipoprotein (a)) concentrations are widely genetically determined by the
LPA isoforms and show 5-fold interpopulation differences. Two-to 3-fold differences have …

High degree of genetic polymorphism in apolipoprotein (a) associated with plasma lipoprotein (a) levels in Japanese and Chinese populations

S Kikuchi, A Nakagawa, K Kobayashi, L Li, H Yanagi… - Human genetics, 1993 - Springer
We have developed a sensitve, high-resolution method for the analysis of the apolipoprotein
(a)[apo (a)] isoforms using sodium dodecyl sulfate (SDS)-agarose/gradient polyacrylamide …