Predictors of mosaic chromosome Y loss and associations with mortality in 223,338 men of the UK Biobank
Mosaic loss of the Y chromosome (mLOY) in peripheral leukocytes is an age-related event
commonly observed in men older than 50 years of age in which a fraction of leukocytes …
commonly observed in men older than 50 years of age in which a fraction of leukocytes …
[HTML][HTML] Predictors of mosaic chromosome Y loss and associations with mortality in the UK Biobank
Mosaic loss of the Y chromosome (mLOY) is the most commonly reported large structural
somatic event. Previous studies have indicated age and cigarette smoking increase the risk …
somatic event. Previous studies have indicated age and cigarette smoking increase the risk …
[HTML][HTML] Mosaic chromosome Y loss is associated with alterations in blood cell counts in UK Biobank men
Mosaic loss of Y chromosome (mLOY) is the most frequently detected somatic copy number
alteration in leukocytes of men. In this study, we investigate blood cell counts as a potential …
alteration in leukocytes of men. In this study, we investigate blood cell counts as a potential …
Mosaic Y loss is moderately associated with solid tumor risk
Mosaic loss of the Y chromosome (mLOY) in peripheral leukocytes is a somatic event in
which a fraction of leukocytes have lost the entire Y chromosome. The frequency of mLOY …
which a fraction of leukocytes have lost the entire Y chromosome. The frequency of mLOY …
Mosaic loss of the Y chromosome is associated with prostate cancer risk
RL Kelly, W Zhou, KM Barnao, CD Young, AK Hubbard… - Cancer Research, 2024 - AACR
Mosaic loss of the Y chromosome (mLOY), a type of clonal hematopoiesis, is the most
frequent chromosomal alteration observed in leukocytes of aging men. mLOY is a putative …
frequent chromosomal alteration observed in leukocytes of aging men. mLOY is a putative …
Confusing cause with effect: the correlation of chromosome Y loss in older men with elevated cancer and mortality risk
R Stindl - Authorea Preprints, 2023 - advance.sagepub.com
Confusing cause with effect: the correlation of chromosome Y loss in older men with
elevated cancer and mortality risk Page 1 P osted on 17 Apr 2023 — The cop yrigh t holder …
elevated cancer and mortality risk Page 1 P osted on 17 Apr 2023 — The cop yrigh t holder …
[HTML][HTML] A polygenic risk score predicts mosaic loss of chromosome Y in circulating blood cells
Background Mosaic loss of Y chromosome (LOY) is the most common somatic change that
occurs in circulating white blood cells of older men. LOY in leukocytes is associated with …
occurs in circulating white blood cells of older men. LOY in leukocytes is associated with …
Mosaic loss of chromosome Y in peripheral blood is associated with shorter survival and higher risk of cancer
LA Forsberg, C Rasi, N Malmqvist, H Davies… - Nature …, 2014 - nature.com
Incidence and mortality for sex-unspecific cancers are higher among men, a fact that is
largely unexplained,. Furthermore, age-related loss of chromosome Y (LOY) is frequent in …
largely unexplained,. Furthermore, age-related loss of chromosome Y (LOY) is frequent in …
[HTML][HTML] Longitudinal changes in the frequency of mosaic chromosome Y loss in peripheral blood cells of aging men varies profoundly between individuals
M Danielsson, J Halvardson, H Davies… - European Journal of …, 2020 - nature.com
Mosaic loss of chromosome Y (LOY) is the most common somatic genetic aberration and is
associated with increased risk for all-cause mortality, various forms of cancer and …
associated with increased risk for all-cause mortality, various forms of cancer and …
[HTML][HTML] The role of hematopoietic chromosome Y loss in health and disease
J Mattisson - 2023 - diva-portal.org
Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine
1939. 94 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-513-1788-5. Mosaic loss …
1939. 94 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-513-1788-5. Mosaic loss …