In monocytes, the fimbriae of the oral pathogen Porphyromonas gingivalis activate cross talk
signaling from Toll-like receptor 2 (TLR2) to the β2 integrin CD11b/CD18, leading to the …

Interaction between the major fimbriae of Porphyromonas gingivalis and gingival epithelial
cells is important for bacterial adhesion and invasion. In this study, we identified integrins as …

In this study, we demonstrate that Porphyromonas gingivalis fimbriae use molecules of β2
integrin (CD11/CD18) on mouse peritoneal macrophages as cellular receptors and also …

In monocytes and macrophages, the interaction of Porphyromonas gingivalis with Toll‐like
receptor 2 (TLR 2) leads to the activation of a MyD88‐dependent antimicrobial pathway and …

CD11b–CD18 and other integrins play important roles in immunity and inflammation and
require prior activation through inside‐out signaling to efficiently bind their ligands. We …

Toll‐like receptors (TLRs) and other pattern‐recognition receptors (PRRs) of the innate
immune system form functional receptor complexes that recognize and respond to pathogen …

Porphyromonas gingivalis is a predominant periodontal pathogen, whose fimbriae are
considered to be a major virulence factor, especially for bacterial adherence and invasion of …

Humans develop periodontitis in response to challenge by microbial dental plaque.
Inflammation begins after perturbation of gingival epithelial cells by subgingival bacteria …

Porphyromonas gingivalis is an oral pathogen that has recently been associated with
chronic inflammatory diseases such as atherosclerosis. The strength of the epidemiological …

The adherence of Porphyromonas gingivalis to host cells is likely a prerequisite step in the
pathogenesis of P. gingivalis-induced periodontal disease. P. gingivalis binds to and …