Left ventricular hypertrophy (LVH) is an independent cardiovascular risk factor. Angiotensin
AT1 receptor antagonism has been considered as a specific approach to block the renin …

Roles of angiotensin II (Ang II) in the regulation of cardiovascular system under normal and
pathological condition have been well documented. Although two major subtypes of Ang II …

Angiotensin II modulates beat-to-beat cardiac performance as a potent vasocontrictor,
inotrope, and regulator of water and electrolyte balance. It is also a growth factor that can …

Left ventricular hypertrophy (LVH) is considered a major predictor of cardiovascular
morbidity and mortality. While it is unanimously accepted that the angiotensin AT1 receptor …

Angiotensin II (Ang II) is considered the major final mediator of the renin-angiotensin system.
The actions of Ang II have been implicated in many cardiovascular conditions, such as …

There are two subtypes of angiotensin (Ang) II receptors, AT1R and AT2R. It is established
that clinical use of specific AT1R blocker (ARB) improves the long-term prognosis of heart …

Background—The precise function of angiotensin II type 2 receptor (AT2-R) in the
mammalian heart in vivo is unknown. Here, we investigated the role of AT2-R in cardiac …

To determine distribution and function of cardiac angiotensin (ANG) II receptor AT1 and AT2
subtypes in left ventricular (LV) hypertrophy (LVH), ANG II (10 (-8) M) was infused into …

Angiotensin II (Ang II) has important actions on the heart via type 1 (AT1) and type 2 (AT2)
receptors. The link between AT1 receptor activation and the hypertrophy of cardiomyocytes …

Angiotensin II (Ang II) has multiple actions in the heart that affect cardiac remodeling and
contractility, most of which can be attributed to activation of the Ang II type-1 (AT1) receptor …