M emory T-cell responses are of vital importance in understanding the host's immune
response against pathogens and cancer cells and to begin establishing the correlation of …

A critical aim of vaccine‐related research is to identify the mechanisms by which memory T
cells are formed and maintained over long periods of time. In recent years, we have …

Immunological memory is one of the features that define the adaptive immune response: by
generating specific memory cells after infection or vaccination, the host provides itself with a …

Vaccines, arguably the single most important intervention in improving human health, have
exploited the phenomenon of immunological memory. The elicitation of memory T cells is …

The immune system has adapted to effect different mechanisms to combat the multitude of
potential pathogens in our environment. In particular, CD8 T cells are participants in the …

Protection against intracellular pathogens or tumor antigens requires T-cell mediated
responses. Recently, it has become apparent that protection against disease correlates with …

Adequate antigen stimulation can lead to permanent modifications of primed cells and to the
generation of memory T cells that have astonishingly improved capacities to deal with …

CD8 T cells are an important part of the adaptive immune system providing protection
against intracellular bacteria, viruses, and protozoa. After infection and/or vaccination …

Immunity towards intracellular pathogens is often dependent upon the generation of CD8+
memory T cells, which provide long-lasting and effective protection. Over the past few years …

CD4 T-cell memory is in some ways more enigmatic than CD8 T-cell memory. This is mostly
due to the fact that CD4 T cells tend to expand far less in response to antigenic stimuli …