Supplementation of fat grafts with adipose-derived regenerative cells improves long-term graft retention

M Zhu, Z Zhou, Y Chen, R Schreiber… - Annals of plastic …, 2010 - journals.lww.com
Current practice of autologous fat transfer for soft tissue augmentation is limited by poor long-
term graft retention. Adipose-derived regenerative cells (ADRCs) contain several types of …

Prevalence of endogenous CD34+ adipose stem cells predicts human fat graft retention in a xenograft model

BJ Philips, TL Grahovac, JE Valentin… - Plastic and …, 2013 - journals.lww.com
Background: Fat grafting is a promising technique for soft-tissue augmentation, although
graft retention is highly unpredictable and factors that affect graft survival have not been well …

Enrichment of autologous fat grafts with ex-vivo expanded adipose tissue-derived stem cells for graft survival: a randomised placebo-controlled trial

SFT Kølle, A Fischer-Nielsen, AB Mathiasen, JJ Elberg… - The Lancet, 2013 - thelancet.com
Background Autologous fat grafting is increasingly used in reconstructive surgery. However,
resorption rates ranging from 25% to 80% have been reported. Therefore, methods to …

Differential contributions of graft-derived and host-derived cells in tissue regeneration/remodeling after fat grafting

K Doi, F Ogata, H Eto, H Kato, S Kuno… - Plastic and …, 2015 - journals.lww.com
Background: Recent research indicates that the adipose tissue of nonvascularized grafts is
completely remodeled within 3 months, although origins of next-generation cells are …

Paracrine mechanism of angiogenesis in adipose-derived stem cell transplantation

H Suga, JP Glotzbach, M Sorkin… - Annals of plastic …, 2014 - journals.lww.com
Methods We isolated and cultured ASCs from transgenic mice that express both luciferase
and green fluorescent protein and injected the cells into the inguinal fat pads of wild-type …

Studies in fat grafting: Part IV. Adipose-derived stromal cell gene expression in cell-assisted lipotransfer

RM Garza, RC Rennert, KJ Paik… - Plastic and …, 2015 - journals.lww.com
Background: Fat graft volume retention remains highly unpredictable, but addition of
adipose-derived stromal cells to fat grafts has been shown to improve retention. The present …

Fat grafting versus adipose-derived stem cell therapy: distinguishing indications, techniques, and outcomes

CJ Tabit, GC Slack, K Fan, DC Wan, JP Bradley - Aesthetic plastic surgery, 2012 - Springer
With adipose-derived stem cells (ASCs) at the forefront of research and potential clinical
applications, it is important that clinicians be able to distinguish them from the fat grafting …

Staged stem cell-enriched tissue (SET) injections for soft tissue augmentation in hostile recipient areas: a preliminary report

T Tiryaki, N Findikli, D Tiryaki - Aesthetic Plastic Surgery, 2011 - Springer
Background Autologous fat transplantation is frequently used for a variety of cosmetic
treatments and difficult reconstructive indications such as involutional disorders, hemifacial …

Improvement of the survival of human autologous fat transplantation by using VEGF-transfected adipose-derived stem cells

F Lu, J Li, JH Gao, R Ogawa, C Ou… - Plastic and …, 2009 - journals.lww.com
Background: The efficacy of autologous fat transplantation is reduced by fat absorption and
fibrosis due to fat necrosis. Enhanced transplant neovascularization early after …

How does fat survive and remodel after grafting?

T Mashiko, K Yoshimura - Clinics in plastic surgery, 2015 - plasticsurgery.theclinics.com
Adipose tissue and adipose-derived stem/stromal cells (ASCs) obtained from liposuction
were shown to have potential for regenerative therapeutic use. However, clinical outcomes …