One of the major challenges modern nephrology should face is the identification of
biomarkers that are associated with histopathological patterns or defined pathogenic …

Glomerulonephritis (GN) is one of the most common origins of chronic kidney disease and
its careful evaluation is crucial for prognostic and therapeutic purposes, with the renal biopsy …

Recent advances in glomerular biology have expanded our understanding of glomerular
diseases, leading to more precise therapeutic options. Since the discovery of the …

Proteomic biomarkers offer the hope of improving the management of patients with kidney
diseases by enabling more accurate and earlier detection of renal pathology than is …

The World Health Organization has estimated mortality and burden of chronic kidney
disease (CKD) in 2002 and predicted it will rank 13th in 2030 instead of 17th in 2002 among …

In the past decade there has been a sea change in the way disease is diagnosed and
investigated due to the advent of high throughput technologies, such as microarrays, lab on …

Introduction Chronic kidney disease is avery common and complex chronic disease.
Uncovering the pathological patterns of CKD on the molecular level of bio-fluids and tissue …

A growing number of patients are recognised to have chronic kidney disease (CKD).
However, only a minority will progress to end‐stage renal disease requiring dialysis or …

Proteomics is widely envisioned as playing a significant role in the translation of genomics to
clinically useful applications, especially in the areas of diagnostics and prognostics. In the …

The diagnosis and treatment of glomerular diseases are now based primarily on clinical
manifestations, urinary protein excretion levels and renal histology. Renal biopsy is an …