[HTML][HTML] Fine particulate matter induces airway inflammation by disturbing the balance between Th1/Th2 and regulation of GATA3 and Runx3 expression in BALB/c …

L Pang, P Yu, X Liu, Y Fan… - Molecular medicine …, 2021 - spandidos-publications.com
The present study aimed to examine the effects of 2.5 µm particulate matter (PM2. 5) on
airway inflammation and to investigate the possible underlying mechanism. Specifically, the …

Fine particulate matter aggravates allergic airway inflammation through thymic stromal lymphopoietin activation in mice

Y Liu, GZ Feng, Q Du, XX Jin… - Molecular Medicine …, 2017 - spandidos-publications.com
Abstract Fine particulate matter (PM2. 5) has been linked to exacerbation of allergic airway
inflammation in mice. However, the mechanism underlying exposure to PM2. 5 and …

Fine particulate matter-induced exacerbation of allergic asthma via activation of T-cell immunoglobulin and mucin domain 1

YX Zhao, HR Zhang, XN Yang, YH Zhang… - Chinese Medical …, 2018 - mednexus.org
Background: Fine particulate matter (PM2. 5) exacerbates airway inflammation and
hyperreactivity in patients with asthma, but the mechanism remains unclear. The aim of this …

Effects of airborne fine particulate matters on pulmonary inflammation injury and Th17/Treg balance of sub-chronic exposure mice

L Yang, Q Ma, L Li, P Lü, R Jiang… - Wei Sheng yan jiu …, 2014 - europepmc.org
Objective To explore effects of fine particulate matters (PM 2.5) onpulmonary inflammation,
and the changes of Th17/Treg balance as well as related cytokines. Method Thirty-two …

[HTML][HTML] The effect of size-segregated ambient particulate matter on Th1/Th2-like immune responses in mice

KL Huang, SY Liu, CCK Chou, YH Lee, TJ Cheng - PLoS One, 2017 - journals.plos.org
Background Particulate matter (PM) has been associated with increased pulmonary and
cardiovascular mortality and morbidity. Additionally, PM is known to exacerbate asthma …

PM2. 5 aggravates airway inflammation in asthmatic mice: activating NF-κB via MyD88 signaling pathway

L Wang, Y Cui, H Liu, J Wu, J Li… - International Journal of …, 2023 - Taylor & Francis
The role of PM2. 5 in the bronchial asthma remains unclear. In this study, the deficient mice
of TLR4-/-, TLR2-/-and MyD88-/-were used to establish asthma model. The effects of PM2. 5 …

Fine particulate matter promotes airway inflammation and mucin production by activating endoplasmic reticulum stress and the IRE1α/NOD1/NF‑κB pathway

L Hu, C Xu, X Tang, S Yu… - International …, 2023 - spandidos-publications.com
Abstract Fine particulate matter (PM2. 5) is a type of small particle that is< 2.5 µm in diameter
that may cause airway inflammation. Thus, the present study aimed to explore the effects of …

Subacute exposure of PM2. 5 induces airway inflammation through inflammatory cell infiltration and cytokine expression in rats

Y Li, B Sun, Y Shi, J Jiang, Z Du, R Chen, J Duan… - Chemosphere, 2020 - Elsevier
Accumulating evidences support that exposure to fine particulate matter (PM 2.5) could
cause inflammation of the airway, but its underlying mechanisms are less known. Our study …

Epigenetic regulation is involved in traffic-related PM2. 5 aggravating allergic airway inflammation in rats

C Wang, J Wang, X Zheng, J Zhang, J Zhang, G Qiao… - Clinical …, 2022 - Elsevier
Increasing fine particulate matter (PM 2.5) and epigenetic modifications are closely
associated with the pathogenesis of asthma, but the definite mechanism remains unclear …

PM2. 5 and water-soluble components induce airway fibrosis through TGF-β1/Smad3 signaling pathway in asthmatic rats

H Wu, D Wang, H Shi, N Liu, C Wang, J Tian… - Molecular …, 2021 - Elsevier
Epidemiological studies have suggested that fine particulate matter (PM 2.5) and asthma
have been independently associated with pulmonary fibrosis but rarely studied together …