In many subjects who are genetically susceptible to asthma, exposure to environmental
stimuli may exacerbate their condition. However, it is unknown how the expression and …

Dendritic cells (DC) have a central role in the initiation of adequate immune responses. They
recognize pathogens by means of Toll-like receptors (TLR) and link innate to adaptive …

Exposure to airborne particulate matter (PM) is a major risk factor for allergic airway
inflammation such as asthma. Many of the PM components (ie, polycyclic aromatic …

BACKGROUND: Laboratory and epidemiological studies have provided indirect but
compelling evidence that Toll-like receptors (TLRs) play an important role in innate host …

BACKGROUND: Dendritic cells (DCs) translate environmental cues into T-cell activating
signals, and are centrally involved in allergic airway inflammation. Ambient particulate …

The link between air pollution and adverse pulmonary health effects is well established. The
National Ambient Air Quality Standards were formulated to protect human health. These …

Exposure to urban particulate matter (UPM) exacerbates asthmatic lung inflammation. Lung
dendritic cells (DCs) are critical for stimulating T cell immunity and in maintaining airway …

The immune responses play a profound role in the progression of lung lesions in both
infectious and non-infectious diseases. Dendritic cells, as the" frontline" immune cells …

Ambient particulate matter, including diesel exhaust particles (DEP), promotes the
development of allergic disorders. DEP increase oxidative stress and influence human …

Organic dust exposure in agricultural environments results in significant airway inflammatory
diseases. Gram-positive cell wall components are present in high concentrations in animal …