BACKGROUND The objective of this study was to update the registry of women in the
Netherlands with clear cell adenocarcinoma (CCAC) of the cervix or vagina with or without …

Intrauterine diethylstilbestrol (DES) exposure is associated with an increased risk for the
development of clear cell adenocarcinoma (CCA) of the vagina and cervix. The age of the …

Currently, over 400 cases of clear cell adenocarcinoma of the vagina and cervix occurring in
females born after 1940 have been accessioned into the Registry for Research on Hormonal …

Although the association between in utero exposure to diethylstilbestrol (DES) and clear cell
adenocarcinoma of the cervix and vagina (CCA) was first reported among young women …

Abstract The Central Netherlands Registry (CNR) of women with vaginal or cervical clear
cell adenocarcinoma (CCAC) was established in 1985. An overview is presented of clinical …

Most young women with clear-cell adenocarcinoma (CCA) of the vagina have a history of
prenatal exposure to diethylstilbestrol (DES). Some, however, develop vaginal CCA without …

Abstract In May 1999, an 18-year-old woman visited a physician because of vaginal
bleeding and the excretion of large clots from the vagina. A vaginal tumor was discovered …

Objective Women exposed to diethylstilbestrol (DES) in utero are at increased risk for the
development of vaginal and cervical clear cell adenocarcinoma (CCA) at younger age. It is …

This study was based on cases accessioned in the Registry of Clear Cell Adenocarcinoma
of the Genital Tract in Young Females to ascertain the incidence of diethylstilbestrol (DES) …

Three hundred and eighty-four cases of clear cell adenocarcinoma of the vagina and cervix
accessioned into the Registry as of December 31, 1978, have been analyzed. The annual …