[HTML][HTML] High-fat diet-induced memory impairment in triple-transgenic Alzheimer's disease (3xTgAD) mice is independent of changes in amyloid and tau pathology
EM Knight, IVA Martins, S Gümüsgöz, SM Allan… - Neurobiology of …, 2014 - Elsevier
Obesity and consumption of a high-fat diet are known to increase the risk of Alzheimer's
disease (AD). Diets high in fat also increase disease neuropathology and/or cognitive …
disease (AD). Diets high in fat also increase disease neuropathology and/or cognitive …
[HTML][HTML] Mitochondrial abnormalities and synaptic loss underlie memory deficits seen in mouse models of obesity and Alzheimer's disease
Obesity is associated with impaired memory in humans, and obesity induced by high-fat
diets leads to cognitive deficits in rodents and in mouse models of Alzheimer's disease (AD) …
diets leads to cognitive deficits in rodents and in mouse models of Alzheimer's disease (AD) …
High-fat diet aggravates amyloid-beta and tau pathologies in the 3xTg-AD mouse model
To investigate potential dietary risk factors of Alzheimer's disease (AD), triple transgenic
(3xTg-AD) mice were exposed from 4 to 13 months of age to diets with a low n-3: n-6 …
(3xTg-AD) mice were exposed from 4 to 13 months of age to diets with a low n-3: n-6 …
[HTML][HTML] Sex-specific effects of high fat diet on indices of metabolic syndrome in 3xTg-AD mice: implications for Alzheimer's disease
AM Barron, ER Rosario, R Elteriefi, CJ Pike - PloS one, 2013 - journals.plos.org
Multiple factors of metabolic syndrome have been implicated in the pathogenesis of
Alzheimer's disease (AD), including abdominal obesity, insulin resistance, endocrine …
Alzheimer's disease (AD), including abdominal obesity, insulin resistance, endocrine …
Hypermetabolism in a triple-transgenic mouse model of Alzheimer's disease
EM Knight, A Verkhratsky, SM Luckman, SM Allan… - Neurobiology of …, 2012 - Elsevier
A common feature of Alzheimer's disease (AD) is weight loss, even though there is often an
increase in food intake in AD patients. The reasons for this weight loss are unknown, but …
increase in food intake in AD patients. The reasons for this weight loss are unknown, but …
Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease
VKM Halagappa, Z Guo, M Pearson, Y Matsuoka… - Neurobiology of …, 2007 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive
decline in cognitive function associated with the neuropathological hallmarks amyloid β …
decline in cognitive function associated with the neuropathological hallmarks amyloid β …
[HTML][HTML] Contributions of a high-fat diet to Alzheimer's disease-related decline: a longitudinal behavioural and structural neuroimaging study in mouse models
CPE Rollins, D Gallino, V Kong, G Ayranci… - NeuroImage: Clinical, 2019 - Elsevier
Obesity is recognized as a significant risk factor for Alzheimer's disease (AD). Studies have
supported that obesity accelerates AD-related pathophysiology and memory impairment in …
supported that obesity accelerates AD-related pathophysiology and memory impairment in …
Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model
C Hirata-Fukae, HF Li, HS Hoe, AJ Gray, SS Minami… - Brain research, 2008 - Elsevier
Epidemiological studies indicate that women have a higher risk of Alzheimer's disease (AD)
even after adjustment for age. Though transgenic mouse models of AD develop AD-related …
even after adjustment for age. Though transgenic mouse models of AD develop AD-related …
Effect of high-fat diet on cognitive impairment in triple-transgenic mice model of Alzheimer's disease
SK Sah, C Lee, JH Jang, GH Park - Biochemical and biophysical research …, 2017 - Elsevier
Abstract High-fat diet (HFD)-induced obesity is a risk factor for cognitive impairment in
Alzheimer's disease (AD). It has been reported that two typical neuropathological markers of …
Alzheimer's disease (AD). It has been reported that two typical neuropathological markers of …
Age‐dependent impairment of glucose tolerance in the 3xTg‐AD mouse model of Alzheimer's disease
Alzheimer's disease (AD) has been associated with type II diabetes (T2D) and obesity in
several epidemiologic studies. To determine whether AD neuropathology can cause …
several epidemiologic studies. To determine whether AD neuropathology can cause …