Apigenin attenuates copper-mediated β-amyloid neurotoxicity through antioxidation, mitochondrion protection and MAPK signal inactivation in an AD cell model
L Zhao, J Wang, Y Wang, X Fa - Brain research, 2013 - Elsevier
Apigenin, belonging to a less toxic and non-mutagenic flavone subclass of flavonoids, has
been reported to possess numerous biological activities beneficial to health. Although …
been reported to possess numerous biological activities beneficial to health. Although …
The flavonoid apigenin protects brain neurovascular coupling against amyloid-β 25-35-induced toxicity in mice
R Liu, T Zhang, H Yang, X Lan… - Journal of Alzheimer's …, 2011 - content.iospress.com
Apigenin, one of the most common flavonoids, has demonstrated anti-inflammatory,
anticarcinogenic, and free radical-scavenging activities. Recent studies revealed its …
anticarcinogenic, and free radical-scavenging activities. Recent studies revealed its …
Hesperidin alleviates cognitive impairment, mitochondrial dysfunction and oxidative stress in a mouse model of Alzheimer's disease
D Wang, L Liu, X Zhu, W Wu, Y Wang - Cellular and molecular …, 2014 - Springer
The role of mitochondrial dysfunction and oxidative stress has been well-documented in
Alzheimer's disease (AD). Bioflavonoids are being utilised as neuroprotectants in the …
Alzheimer's disease (AD). Bioflavonoids are being utilised as neuroprotectants in the …
Neuroprotective, anti-amyloidogenic and neurotrophic effects of apigenin in an Alzheimer's disease mouse model
L Zhao, JL Wang, R Liu, XX Li, JF Li, L Zhang - Molecules, 2013 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by extracellular
senile plaques and intracellular neurofibrillary tangles in the brain. Amyloid-β peptides (Aβ) …
senile plaques and intracellular neurofibrillary tangles in the brain. Amyloid-β peptides (Aβ) …
Vitegnoside mitigates neuronal injury, mitochondrial apoptosis, and inflammation in an Alzheimer's disease cell model via the p38 MAPK/JNK pathway
Q Wang, H Jiang, L Wang, H Yi, Z Li… - Journal of Alzheimer's …, 2019 - content.iospress.com
Alzheimer's disease (AD) is a chronic neurodegenerative disorder characterized by
progressive cognitive impairments. Vitegnoside is a flavonoid present in the medicinal plant …
progressive cognitive impairments. Vitegnoside is a flavonoid present in the medicinal plant …
Protective effects of hesperidin against amyloid-β (Aβ) induced neurotoxicity through the voltage dependent anion channel 1 (VDAC1)-mediated mitochondrial …
DM Wang, SQ Li, XY Zhu, Y Wang, WL Wu… - Neurochemical …, 2013 - Springer
Amyloid-β (Aβ) is known to exert cytotoxic effects by inducing mitochondrial dysfunction.
Additionally, the mitochondrial voltage-dependent anion channel 1 (VDAC1), which is …
Additionally, the mitochondrial voltage-dependent anion channel 1 (VDAC1), which is …
[HTML][HTML] Protective role of apigenin against Aβ 25–35 toxicity via inhibition of mitochondrial cytochrome c release
F Nikbakht, Y Khadem, S Haghani… - Basic and Clinical …, 2019 - ncbi.nlm.nih.gov
Methods: Intracerebroventricular (ICV) microinjection of Aβ 25–35 was used for AD
modeling. Working memory was assessed 21 days later using the Y maze test. Neuronal …
modeling. Working memory was assessed 21 days later using the Y maze test. Neuronal …
Inhibition of beta-amyloid-induced neurotoxicity by pinocembrin through Nrf2/HO-1 pathway in SH-SY5Y cells
Y Wang, Y Miao, AZ Mir, L Cheng, L Wang… - Journal of the …, 2016 - Elsevier
Amyloid beta peptide (Aβ) can cause neurotoxicity in Alzheimer's disease (AD). It evokes a
cascade of oxidative damage to neurons. Pinocembrin (PCB), the most abundant flavonoid …
cascade of oxidative damage to neurons. Pinocembrin (PCB), the most abundant flavonoid …
[PDF][PDF] Nicotine attenuates the β‐amyloid neurotoxicity through regulating metal homeostasis
Accumulative evidence indicates nicotine has therapeutic effect for Alzheimer's disease
(AD), but the mechanism of reducing-amyloidosis by nicotine is not clear. The abnormal …
(AD), but the mechanism of reducing-amyloidosis by nicotine is not clear. The abnormal …
Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling …
Background It is known that amyloid-β peptide (Aβ) plays a pivotal role in the pathogenesis
of Alzheimer's disease (AD). Interaction between Aβ and the receptor for advanced glycation …
of Alzheimer's disease (AD). Interaction between Aβ and the receptor for advanced glycation …