Type 2 diabetes is a serious, genetically influenced disease for which no fully effective
treatments are available. Identification of biochemical or regulatory pathways involved in the …

Considerable evidence supports a major inherited component of type 2 diabetes. We initially
conducted a genome-wide scan with 440 microsatellite markers at 10-cM intervals in 19 …

Despite recent advances in the molecular genetics of type 2 diabetes, the majority of
susceptibility genes in humans remain to be identified. We therefore conducted a 10-cM …

The prevalence of type 2 diabetes among Australian residents is 7.5%; however, prevalence
rates up to six times higher have been reported for indigenous Australian communities …

Type 2 diabetes refers to a group of disparate metabolic diseases, which are typically
characterized by insulin resistance in peripheral tissues, together with impaired insulin …

Since little is known about chromosomal locations harboring type 2 diabetes–susceptibility
genes, we conducted a genomewide scan for such genes in a Mexican American …

Improved molecular understanding of the pathogenesis of type 2 diabetes is essential if
current therapeutic and preventative options are to be extended. To identify diabetes …

African Americans are at increased risk of type 2 diabetes and many diabetes complications.
We have carried out a genome-wide scan for African American type 2 diabetes using 638 …

We undertook a genome-wide scan using 190 markers with an average separation of 20 cM
in 49 Canadian Oji-Cree sib pairs affected with type 2 diabetes. Four of these markers, one …

Aims/hypothesis Over 50 regions of the genome have been associated with type 1 diabetes
risk, mainly using large case/control collections. In a recent genome-wide association (GWA) …