The impact of allodynia on the efficacy of almotriptan when given early in migraine: data from the “act when mild” study

S Diaz-Insa, PJ Goadsby, G Zanchin… - International Journal …, 2011 - Taylor & Francis
The objective of this study was to evaluate the impact of allodynia on treatment outcomes in
the patients with acute migraine treated in the “Act when Mild”(AwM) study. AwM, a …

Efficacy, speed of action and tolerability of almotriptan in the acute treatment of migraine: pooled individual patient data from four randomized, double-blind, placebo …

CG Dahlöf, J Pascual, DW Dodick… - Cephalalgia, 2006 - journals.sagepub.com
A meta-analysis of pooled individual patient data from four randomized, placebo-controlled,
double-blind trials comparing several doses of almotriptan (n= 1908) with placebo (n= 386) …

Early intervention with almotriptan improves sustained pain‐free response in acute migraine

NT Mathew - Headache: The Journal of Head and Face Pain, 2003 - Wiley Online Library
Objective.—To determine whether treatment of migraine with almotriptan, when pain
intensity is mild, improves 1‐and 2‐hour pain‐free and sustained pain‐free rates compared …

Almotriptan increases sustained pain‐free outcomes in acute migraine: results from three controlled clinical trials

DW Dodick - Headache: The Journal of Head and Face Pain, 2002 - Wiley Online Library
Objective.—Evaluate the effect of almotriptan on sustained pain‐free outcome in patients
with acute migraine. Methods.—Three randomized, double‐blind, placebo‐controlled trials …

Consistent efficacy and tolerability of almotriptan in the acute treatment of multiple migraine attacks: results of a large, randomized, double-blind, placebo-controlled …

J Pascual, RM Falk, F Piessens, A Prusinski… - …, 2000 - journals.sagepub.com
In this double-blind study, the efficacy and tolerability of a single dose of almotriptan (6.25 or
12.5 mg) was compared with placebo in the treatment of three consecutive migraine attacks …

Almotriptan for the treatment of acute migraine: a review of early intervention trials

F Antonaci, I De Cillis, MG Cuzzoni… - Expert review of …, 2010 - Taylor & Francis
Almotriptan is a serotonin (5-hydroxytryptamine) 1B/1D receptor agonist (triptan) that has
shown consistent efficacy in the acute treatment of migraine with excellent tolerability. It is an …

Influence of trigger factors on the efficacy of almotriptan as early intervention for the treatment of acute migraine in a primary care setting: the START study

M Leone, C Vila, C McGown - Expert review of neurotherapeutics, 2010 - Taylor & Francis
In a large observational general practice study (the Standardized Study with Almotriptan in
Early Treatment of Migraine [START]), 12.5 mg almotriptan administered within 1 h of pain …

Crossover, double‐blind clinical trial comparing almotriptan and ergotamine plus caffeine for acute migraine therapy

MJA Láinez, J Galvan, J Heras… - European journal of …, 2007 - Wiley Online Library
In this randomized, double‐blind, crossover clinical trial, adult patients treated two migraine
attacks: one with almotriptan 12.5 mg and the other with ergotamine 2 mg plus caffeine 200 …

Early vs. non-early intervention in acute migraine—'Act when Mild (AwM)'. A double-blind, placebo-controlled trial of almotriptan

PJ Goadsby, G Zanchin, G Geraud… - …, 2008 - journals.sagepub.com
The study was designed to compare the response to almotriptan in migraine patients who
take medication early in the course of the attack with that when medication is taken after pain …

Allodynia‐associated symptoms, pain intensity and time to treatment: Predicting treatment response in acute migraine intervention

RK Cady, FG Freitag, NT Mathew… - … : The Journal of …, 2009 - Wiley Online Library
Objective.—To evaluate the relationship between treatment outcomes and allodynia‐
associated symptoms (AAS) at the time of treatment with almotriptan. Methods.—Analyses …