Background: Obesity is a chronic progressive disease with several metabolic alterations.
Nonalcoholic fatty liver disease (NAFLD) is an important comorbidity of obesity that can …

Excessive energy intake greatly contributes to the development of nonalcoholic fatty liver
disease (NAFLD) in modern society. To better understand the comprehensive mechanisms …

Abstract Background and aims Even Non-alcoholic steatohepatitis (NASH) has been
becoming the key role in process of liver fibrosis or cirrhosis, no any NASH involving liver …

There are varieties of murine models of nonalcoholic steatohepatitis (NASH) with different
pathophysiologic characteristics. For preclinical assessment, a standardized model would …

Overfeeding of a hypercaloric diet leads to obesity, diabetes, chronic inflammation, and fatty
liver disease. Although limiting fat or carbohydrate intake is the cornerstone for obesity …

Non-alcoholic fatty liver disease (NAFLD) pathogenesis remains poorly understood due to
the complex metabolic and inflammatory changes in the liver. This study aimed to elucidate …

Background General overnutrition is one of the key factors involved in the development of
nonalcoholic fatty liver disease (NAFLD) as the most common liver disease occur by two …

Background Non-alcoholic fatty liver disease (NAFLD) is a hepatic manifestation of
metabolic syndrome. Within the spectrum of NAFLD, non-alcoholic steatohepatitis (NASH) in …

The objective of this study was to develop a well-characterized mouse model of
nonalcoholic steatohepatitis (NASH) with a strong manifestation of liver fibrosis. The …

Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of metabolic
syndrome, ranging from simple steatosis to non-alcoholic steatohepatitis (NASH) particularly …