Italian multicentre observational study of the prevalence of CCSVI in multiple sclerosis (CoSMo study): rationale, design, and methodology

G Comi, MA Battaglia, A Bertolotto, M Del Sette… - Neurological …, 2013 - Springer
Chronic cerebro-spinal venous insufficiency (CCSVI) has been proposed as a “congenital
malformation” implicated in the pathogenesis of multiple sclerosis (MS). However, numerous …

Observational case-control study of the prevalence of chronic cerebrospinal venous insufficiency in multiple sclerosis: results from the CoSMo study

G Comi, MA Battaglia, A Bertolotto… - Multiple Sclerosis …, 2013 - journals.sagepub.com
Background: Chronic cerebrospinal venous insufficiency (CCSVI) has been proposed as a
possible cause of multiple sclerosis (MS). Objectives: The CoSMo study evaluated the …

Chronic cerebrospinal venous insufficiency in multiple sclerosis: clinical correlates from a multicentre study

S Bastianello, A Romani, G Viselner, EC Tibaldi… - BMC neurology, 2011 - Springer
Background Chronic cerebrospinal venous insufficiency (CCSVI) has recently been reported
to be associated with multiple sclerosis (MS). However, its actual prevalence, possible …

CCSVI deconstructed and discarded

F Barkhof, MP Wattjes - Nature Reviews Neurology, 2013 - nature.com
Chronic cerebrospinal venous insufficiency (CCSVI) has been proposed as a cause of
multiple sclerosis (MS). However, two new studies found a very low overall prevalence of …

Chronic cerebrospinal venous insufficiency is not associated with multiple sclerosis and its severity: a blind-verified study

MA Leone, O Raymkulova, P Naldi, P Lochner… - PLoS …, 2013 - journals.plos.org
Background Chronic Cerebrospinal Venous Insufficiency (CCSVI) has been associated with
multiple sclerosis (MS) with a risk ranging from as high as two-hundred-fold to a protective …

CCSVI and MS: a statement from the European Society of neurosonology and cerebral hemodynamics

C Baracchini, JM Valdueza, M Del Sette, G Baltgaile… - Journal of …, 2012 - Springer
To systematically review the ultrasonographic criteria proposed for the diagnosis of chronic
cerebrospinal venous insufficiency (CCSVI). The authors analyzed the five ultrasonographic …

Multiple sclerosis and CCSVI: a population-based case control study

F Patti, A Nicoletti, C Leone, S Messina, E D'Amico… - 2012 - journals.plos.org
Background Chronic cerebrospinal venous insufficiency (CCSVI) has been associated to
multiple sclerosis (MS). Objective To evaluate the possible association between CCSVI and …

CCSVI is associated with multiple sclerosis

S Morovic, P Zamboni - Neurological research, 2012 - Taylor & Francis
Objectives: To analyze all the arguments against chronic cerebrospinal venous insufficiency
(CCSVI) as a medical entity, and its association with multiple sclerosis (MS) and to revise all …

Proposed chronic cerebrospinal venous insufficiency criteria do not predict multiple sclerosis risk or severity

D Centonze, R Floris, M Stefanini, S Rossi… - Annals of …, 2011 - Wiley Online Library
Objective: It is still unclear whether chronic cerebrospinal venous insufficiency (CCSVI) is
associated with multiple sclerosis (MS), because substantial methodological differences …

Chronic cerebrospinal venous insufficiency in multiple sclerosis: a highly prevalent age-dependent phenomenon

R Lanzillo, M Mancini, R Liuzzi, O Di Donato… - BMC neurology, 2013 - Springer
Background This study aimed to investigate the prevalence and clinical relevance of chronic
cerebrospinal venous insufficiency (CCSVI) in multiple sclerosis (MS) patients and healthy …