Fungal secondary metabolites have important functions for the fungi that produce them, such
as roles in virulence and competition. The hemibiotrophic pine needle pathogen …

In filamentous fungi both pathway-specific and global regulators regulate genes involved in
the biosynthesis of secondary metabolites. LaeA is a global regulator that was named for its …

Plant pathogens use a complex arsenal of weapons, such as toxic secondary metabolites, to
invade and destroy their hosts. Knowledge of how secondary metabolite pathways evolved …

Dothistroma needle blight is one of the most devastating pine tree diseases worldwide. New
and emerging epidemics have been frequent over the last 25 years, particularly in the …

Dothistroma needle blight is a forest disease of increasing international importance due to
its ability to kill as well as to retard the growth of pines. It is caused by fungi in the genus …

Fungi possess genetic systems to regulate the expression of genes involved in complex
processes such as development and secondary metabolite biosynthesis. The product of the …

Genes required for fungal secondary metabolite production are usually clustered, co‐
regulated and expressed in stationary growth phase. Chromatin modification has an …

Dothistroma needle blight is one of the most devastating fungal pine diseases worldwide.
The disease is characterized by accumulation in pine needles of a red toxin, dothistromin …

In fungi, distribution of secondary metabolite (SM) gene clusters is often associated with host-
or environment-specific benefits provided by SMs. In the plant pathogen Alternaria …

Fungal secondary metabolites have many important biological roles and some, like the toxic
polyketide aflatoxin, have been intensively studied at the genetic level. Complete sets of …