Rabbits predominantly rearrange the most 3′ VH gene (VH1); thus combinatorial diversity
is very limited. In man and mouse, the most 3′ DH gene, DQ52, is preferentially rearranged …

In rabbits the 3′-most VH gene (VH1) is predominantly rearranged, limiting combinatorial
diversity. In man and mouse, the 3′-most DH gene, DQ52, is preferentially rearranged early …

The nucleotide sequence of a complete cDNA gene from a DP4-positive HLA-homozygous
cell line, PGF, has been determined. This sequence is identical to the exon sequences in a …

Homozygous lymphoblastoid cell lines representing various Dw subtypes of DR2 were
examined for polymorphism at the DQ β locus by molecular and cellular techniques. The …

The HLA-DP molecules were the last of the HLA class II molecules to be identified. These
molecules were originally detected by the primed lymphocyte test. Their low representation …

A series of 5′ deletion test plasmids barboring promoter sequences of the HLA‐DQβ gene
fused to the bacterial chloramphenicol acetyl transferase (CAT) gene were constructed …

The exons encoding an expressed immunoglobulin (Ig) heavy chain variable region are
assembled from three types of gene segments: variable, Igh-V (Vn), diversity, lgh-D (DH) …

The mouse major histocompatibility complex is composed of several genes arranged into
the K, D, Qa, and Tla regions. The D region of the BALB/c mouse includes genes D2 d, D3 d …

HLA class II genes comprise a large multigene family with intra-and interlocus variation in
structure and expression. Within this family of related genes, the HLA-DX alpha and beta loci …

Abstract A short HIA-DQβ locus-specific (141 bp) probe was cloned from the full-length pII-β-
l cDNA. Pst 1-digested genomic DMA from homozygous typing cell lines (HTC) was …