胰高血糖素样肽1 受体激活: 大脑中的抗炎作用
Y Diz-Chaves, Z Maastor, C Spuch, JA Lamas… - 中国神经再生研究 …, 2024 - sjzsyj.com.cn
The glucagon-like peptide 1 is a pleiotropic hormone that has potent insulinotropic effects
and is key in treating metabolic diseases such as diabetes and obesity. Glucagon-like …
and is key in treating metabolic diseases such as diabetes and obesity. Glucagon-like …
[HTML][HTML] Glucagon-like peptide 1 receptor activation: anti-inflammatory effects in the brain
Y Diz-Chaves, Z Maastor, C Spuch… - Neural Regeneration …, 2024 - journals.lww.com
The glucagon-like peptide 1 is a pleiotropic hormone that has potent insulinotropic effects
and is key in treating metabolic diseases such as diabetes and obesity. Glucagon-like …
and is key in treating metabolic diseases such as diabetes and obesity. Glucagon-like …
[PDF][PDF] 胰高血糖素样肽1 受体激动剂在神经保护方面的研究进展
管天媛， 肖伊宁， 吕佩源 - 国际神经病学神经外科学杂志, 2023 - jinn.org.cn
近年来的研究发现, 与糖尿病并发的多种神经系统疾病, 可随着治疗糖尿病的胰高血糖素样肽1
受体激动剂(GLP⁃ 1RA) 的使用而得到改善, 但其具体机制尚不完全清楚. 天然的GLP⁃ 1 …
受体激动剂(GLP⁃ 1RA) 的使用而得到改善, 但其具体机制尚不完全清楚. 天然的GLP⁃ 1 …
The inactivation of extracellular signal-regulated kinase by glucagon-like peptide-1 contributes to neuroprotection against oxidative stress
S Nakajima, T Numakawa, N Adachi, HS Yoon… - Neuroscience …, 2016 - Elsevier
Abstract Glucagon-like peptide-1 (GLP-1), an insulinotropic peptide secreted from
enteroendocrine cells, has been known to have a neuroprotective effect. However, it is not …
enteroendocrine cells, has been known to have a neuroprotective effect. However, it is not …
GLP-1 的神经保护作用
韩丽萍， 陈莉明 - 国际内分泌代谢杂志, 2016 - cqvip.com
流行病学研究表明, 2 型糖尿病和神经变性疾病, 包括阿尔茨海默病和帕金森病及缺血性脑血管
病存在紧密联系. 这些疾病都存在共同的病理生理学特征, 包括氧化应激, 胰岛素抵抗 …
病存在紧密联系. 这些疾病都存在共同的病理生理学特征, 包括氧化应激, 胰岛素抵抗 …
Glucagon-like peptide-1 cleavage product GLP-1 (9–36) reduces neuroinflammation from stroke via the activation of insulin-like growth factor 1 receptor in astrocytes
J Huang, Y Liu, L Cheng, J Li, T Zhang, G Zhao… - European journal of …, 2020 - Elsevier
Abstract Glucagon-like peptide-1 (GLP-1) is an endogenous gut hormone and a key
regulator in maintaining glucose homeostasis by stimulating insulin secretion. Its natural …
regulator in maintaining glucose homeostasis by stimulating insulin secretion. Its natural …
胰高血糖素样肽-1 及其受体在中枢神经系统的分布和功能
姚红， 郗光霞， 郭敏， 杨娜 - 国际内分泌代谢杂志, 2014 - cqvip.com
胰高糖素样肽-1 (GLP-1) 由中枢神经系统第四脑室边缘的孤束核尾部神经细胞分泌,
后运输至下丘脑室旁核和背侧核. 而其受体在中枢神经系统的分布主要集中在下丘脑 …
后运输至下丘脑室旁核和背侧核. 而其受体在中枢神经系统的分布主要集中在下丘脑 …
[HTML][HTML] Anti-inflammatory effects of GLP-1 receptor activation in the brain in neurodegenerative diseases
Y Diz-Chaves, Z Mastoor, C Spuch… - International Journal of …, 2022 - mdpi.com
The glucagon-like peptide-1 (GLP-1) is a pleiotropic hormone well known for its incretin
effect in the glucose-dependent stimulation of insulin secretion. However, GLP-1 is also …
effect in the glucose-dependent stimulation of insulin secretion. However, GLP-1 is also …
Glucagon-like peptide 1: a novel therapeutic strategy for Alzheimer's disease
XH Wang, W Yang, JS Qi - Sheng li xue bao:[Acta Physiologica …, 2010 - europepmc.org
There is a close correlation between type 2 diabetes mellitus (T2DM) and Alzheimer's
disease (AD) in the course of pathophysiological processes. The neuroprotective action of …
disease (AD) in the course of pathophysiological processes. The neuroprotective action of …
The Role of GLP-1 Affects Fate of Astrocytes Following Ischemic Stroke in Mice
HY Lu, SY Li, JL Yang - Physiology, 2024 - journals.physiology.org
Stroke is one of the leading causes of physical and intellectual disability and mortality in
adults of most of the developed countries. The most of studies in ischemic stroke focus on …
adults of most of the developed countries. The most of studies in ischemic stroke focus on …