Predicting treatable traits for long-acting bronchodilators in patients with stable COPD

J Kang, KT Kim, JH Lee, EK Kim, TH Kim… - … Journal of Chronic …, 2017 - Taylor & Francis
Purpose There is currently no measure to predict a treatability of long-acting β-2 agonist
(LABA) or long-acting muscarinic antagonist (LAMA) in patients with chronic obstructive …

Treatable traits in COPD–a proposed approach

J Cardoso, AJ Ferreira, M Guimarães… - … Journal of Chronic …, 2021 - Taylor & Francis
The well-recognized individual heterogeneity within COPD patients has led to a growing
interest in greater personalization in the approach of these patients. Thus, the treatable traits …

Moving Towards Patient-Centered Medicine for COPD Management: Multidimensional Approaches versus Phenotype-Based Medicine—A Critical View

JL Lopez-Campos, V Bustamante… - COPD: Journal of …, 2014 - Taylor & Francis
For decades, chronic obstructive pulmonary disease (COPD) has been considered a
relentlessly progressive disease in which the deterioration of lung function is associated with …

Can Treatable Traits Be the Approach to Addressing the Complexity and Heterogeneity of COPD?

M Cazzola, P Rogliani, F Blasi - International Journal of Chronic …, 2023 - Taylor & Francis
The complexity of COPD implies the need to identify groups of patients with similar clinical
characteristics and prognosis or treatment requirements. This is why much attention has …

Phenotyping before starting treatment in COPD?

N Siafakas, A Corlateanu, E Fouka - COPD: Journal of Chronic …, 2017 - Taylor & Francis
ABSTRACT Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous and
complex disease with great morbidity and mortality. Despite the new developments in the …

Bronchodilator reversibility in patients with COPD revisited: short-term reproducibility

S Pascoe, W Wu, CQ Zhu, D Singh - International Journal of …, 2016 - Taylor & Francis
Categorization of patients with COPD as reversible or nonreversible to a bronchodilator may
change over time. This post hoc analysis aimed to determine if an individual's reversibility …

COPD phenotypes: differences in survival

J Hernández Vázquez, I Ali García… - … Journal of Chronic …, 2018 - Taylor & Francis
Background The aim of the study was to analyze the characteristics and survival of a group
of patients with COPD according to their clinical phenotype. Patients and methods The study …

Fast decliner phenotype of chronic obstructive pulmonary disease (COPD): Applying machine learning for predicting lung function loss

V Nikolaou, S Massaro, W Garn… - BMJ open …, 2021 - bmjopenrespres.bmj.com
Background Chronic obstructive pulmonary disease (COPD) is a heterogeneous group of
lung conditions challenging to diagnose and treat. Identification of phenotypes of patients …

[HTML][HTML] Chronic obstructive pulmonary disease phenotypes: imprint on pharmacological and non-pharmacological therapy

M Bakeer, GC Funk, A Valipour - Annals of Translational Medicine, 2020 - ncbi.nlm.nih.gov
Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease associated with
significant morbidity and mortality. Over the past few years, there has been cumulating …

Bronchodilator responsiveness as a phenotypic characteristic of established chronic obstructive pulmonary disease

P Albert, A Agusti, L Edwards, R Tal-Singer, J Yates… - Thorax, 2012 - thorax.bmj.com
Background Bronchodilator responsiveness is a potential phenotypic characteristic of
chronic obstructive pulmonary disease (COPD). We studied whether change in lung function …